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  4. MRC71

MRC71 是一种靶向 Halo 标签的 TRIMTAC 降解剂,包含一个 PEG 连接子和一个氯烷烃基团。MRC71 选择性地降解寡聚 CAV1- 和 Cavin1-mEGFP-Halo,而非单体 mEGFP-Halo,并且表现典型的钩状效应浓度依赖性的降解特征。

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MRC71

MRC71 Chemical Structure

CAS No. : 3070832-68-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MRC71 is a TRIMTAC degrader targeting Halo Tag, containing a PEG linker and chloroalkane. MRC71 selectively degrades oligomeric CAV1- and Cavin1-mEGFP-Halo over monomeric mEGFP-Halo and exhibits a characteristic hook effect concentration-dependence for degradation[1].

分子量

816.47

Formula

C43H66ClN5O8

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MRC71
目录号:
HY-180547
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