1. Anti-infection Stem Cell/Wnt
  2. Parasite β-catenin
  3. Murayaquinone

Murayaquinone (PKF118-774) 是一种 β-catenin/Tcf4 复合物抑制剂,其 IC50 为 2.4 μM。Murayaquinone 是一种被发现存在于链霉菌属菌株 AN140557 的杀线虫剂。

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Murayaquinone

Murayaquinone Chemical Structure

CAS No. : 100843-91-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Murayaquinone (PKF118-774) is a β-catenin/Tcf4 complex inhibitor with an IC50 of 2.4 μM. Murayaquinone is a nematicidal agent found in Streptomyces sp. AN140557[1][2].

体外研究
(In Vitro)

Murayaquinone 对 β-catenin/Tcf4 复合物的 IC50 为 2.4 μM[1]
Murayaquinone (3.12-25 μM; 24 h) 表现出显著的剂量依赖性杀线虫活性和抑卵孵化活性[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability AssayWestern Blot AnalysisCell Proliferation AssayApoptosis AnalysisCell Cytotoxicity AssayCell Cycle AnalysisRT-PCRCell Autophagy AssayImmunofluorescenceCell Differentiation AssayCell Invasion AssayCell Migration Assay Real Time qPCRELISA Assay[2]

Cell Line: nematodes and nematodes e ggs
Concentration: 3.12, 6.25, 12.5, and 25 μM
Incubation Time: 24 h
Result: Showed significant dose-dependent nematicidal activity and egg-hatching inhibition.
分子量

324.33

Formula

C19H16O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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产品名称:
Murayaquinone
目录号:
HY-133093
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