1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. N-Desmethyl clindamycin hydrochloride

N-Desmethyl clindamycin hydrochloride 是 Clindamycin (HY-B1455) 的主要代谢产物。N-Desmethyl clindamycin hydrochloride 对 L1210、KB、RPMI 6410 和 RPMI 1788 癌细胞具有强大的细胞毒性,其 LD50 值分别为 0.07、0.29、0.13 和 0.32 μM。N-Desmethyl clindamycin hydrochloride 能够抑制细胞的 DNA、RNA 和蛋白质合成。N-Desmethyl clindamycin hydrochloride 可用于感染和癌症的研究。

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N-Desmethyl clindamycin hydrochloride

N-Desmethyl clindamycin hydrochloride Chemical Structure

CAS No. : 25532-03-0

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生物活性

N-Desmethyl clindamycin hydrochloride is the main metabolite of Clindamycin (HY-B1455). N-Desmethyl clindamycin hydrochloride shows potent cytotoxicity against L1210, KB,RPMI 6410 and RPMI 1788 cancer cells with LD50 values of 0.07, 0.29, 0.13 and 0.32 μM. N-Desmethyl clindamycin hydrochloride can inhibit cell DNA, RNA and protein synthesis. N-Desmethyl clindamycin hydrochloride can be used for the research of infection and cancer[1].

分子量

447.42

Formula

C17H32Cl2N2O5S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
N-Desmethyl clindamycin hydrochloride
目录号:
HY-180469
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