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NE58043 (Compound 21) 是一种含氮双膦酸盐化合物。NE58043 对溶组织内阿米巴 (Entamoeba histolytica) 和恶性疟原虫 (Plasmodium falciparum) 没有显著的抑制活性,其 IC50 值大于 200 μM。NE58043 对人鼻咽癌 KB 细胞的 LD50 值为 171 μM。NE58043 可用于癌症和感染方面的研究,如鼻咽癌。

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NE58043

NE58043 Chemical Structure

CAS No. : 105462-25-7

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  • 生物活性

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生物活性

NE58043 (Compound 21) is a nitrogen-containing bisphosphonate compound. NE58043 has no significant inhibitory activity against Entamoeba histolytica and Plasmodium falciparum with IC50 > 200 μM. NE58043 shows a LD50 of 171 μM for human nasopharyngeal carcinoma KB cells. NE58043 can be used for the research of cancer and infection, such as nasopharyngeal carcinoma[1].

分子量

283.11

Formula

C7H11NO7P2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
NE58043
目录号:
HY-W779743
需求量: