2. 天然产物
  3. 植物 生物碱 萜类
  4. 毛茛科 其他类生物碱 二萜
  5. 准噶尔乌头
  6. Neojiangyouaconitine

Neojiangyouaconitine 是一种二萜生物碱类细胞毒素，可从乌头变种毛竹 (Aconitum soongaricum var. pubescens) 中分离得到。Neojiangyouaconitine 对人乳腺癌、前列腺癌及肺癌细胞具有细胞毒活性，且对 HeLa 细胞的抑制作用较弱。Neojiangyouaconitine 具有对特定肿瘤细胞系的杀伤能力，可应用于乳腺癌、前列腺癌和肺癌等相关癌症机制的研究中。

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Neojiangyouaconitine

Neojiangyouaconitine Chemical Structure

CAS No. : 126266-35-1

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Neojiangyouaconitine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Neojiangyouaconitine is a diterpenoid alkaloid cytotoxin isolated from Aconitum soongaricum var. pubescens. Neojiangyouaconitine exhibits cytotoxic activity against human breast cancer, prostate cancer and lung cancer cells, with weak inhibitory effect on HeLa cells. Neojiangyouaconitine has the ability to kill specific tumor cell lines and can be applied to the research on the mechanisms of related cancers such as breast cancer, prostate cancer and lung cancer[1].

体外研究
(In Vitro)

Neojiangyouaconitine (compound 9) 对 MCF-7、PC-3 和 A549 人肿瘤细胞株具有细胞毒活性，IC50 值分别为 68.7 μM、40.2 μM 和 42.4 μM；而对 HeLa 细胞无细胞毒活性 (IC50>100 μM)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Neojiangyouaconitine 相关抗体:
分子量

601.73

Formula

C33H47NO9
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Neojiangyouaconitine 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Neojiangyouaconitine126266-35-1OthersAconitum soongaricum var. pubescenslung cancerHeLa cellsMCF-7PC-3human lung cancer cellshuman breast cancer cellshuman prostate cancer cellsbreast cancerprostate cancerInhibitorinhibitorinhibit

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