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  3. Isotope-Labeled Compounds
  4. Nicotinamide-15N

Nicotinamide-15N  (Synonyms: 烟酰胺-15N; Niacinamide-15N; Nicotinic acid amide-15N)

目录号: HY-W744757
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Nicotinamide-15N (Niacinamide-15N) 是氘代标记的 Nicotinamide (HY-B0150)。Nicotinamide 是维生素 B3 或烟酸的一种形式。Nicotinamide 可抑制 SIRT2 的活性，其 IC50 值为 2 μM。Nicotinamide 也抑制 SIRT1。Nicotinamide 增加细胞内 NAD+、ATP、ROS 水平。Nicotinamide 抑制肿瘤生长并提高生存率。Nicotinamide Hydrochloride 还具有抗-HBV 活性。

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Nicotinamide-<sup>15</sup>N

Nicotinamide-15N Chemical Structure

CAS No. : 113950-01-9

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Other Forms of Nicotinamide-15N:

Nicotinamide-15N 相关抗体

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  • 生物活性

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生物活性

Nicotinamide-15N (Niacinamide-15N) is the deuterium labeled Nicotinamide (HY-B0150). Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity.

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1. 该化合物可作为示踪剂。
2. 该化合物可作为 NMR、GC-MS 或 LC-MS 分析中的内标品，用于定量分析。
体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Nicotinamide-15N 相关抗体:
分子量

123.12

Formula

C6H6N15NO
CAS 号
非标记 CAS
中文名称

烟酰胺-15N
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Nicotinamide-15N 相关分类

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nicotinamide-15N113950-01-9Niacinamide-15N Nicotinic acid amide-15N烟酰胺-15NIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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