1. Cell Cycle/DNA Damage Epigenetics
  2. PARP
  3. NU 1085

NU 1085 是一种强效的聚 (ADP-核糖) 聚合酶 (PARP) 抑制剂,其 Ki 值为 6 nM。NU 1085 对癌细胞表现出强烈的细胞毒性 (LC50 = 83-94 μM),并且能够增强 Temozolomide (HY-17364) 的抗癌效果。NU 1085 可用于癌症研究,如肺癌。

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NU 1085

NU 1085 Chemical Structure

CAS No. : 188106-83-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NU 1085 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor with a Ki of 6 nM. NU 1085 shows strong cytotoxicity to cancer cells (LC50 = 83-94 μM) and can enhance the anticancer effect of Temozolomide (HY-17364). NU 1085 can be used for the research of cancer, such as lung cancer[1].

分子量

253.26

Formula

C14H11N3O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NU 1085
目录号:
HY-14206
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