2. 多肽产品
  3. 多肽及其衍生物
  4. p5RHH

p5RHH 是一种蜂毒素来源的酸激活型膜裂解肽。p5RHH 可作为 siRNA 递送载体，响应酸性 pH 值启动纳米复合物的同步解组装与内体溶解，在巨胞饮作用后触发 siRNA 释放至细胞质中。

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Custom Peptide Synthesis

p5RHH

p5RHH Chemical Structure

CAS No. : 1423724-82-6

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p5RHH 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

p5RHH is an acid-activated membrane-lytic peptide derived from melittin. p5RHH, as a siRNA delivery vector, initiates synchronous disassembly of nanocomplexes and endosome lysis in response to acidic pH, and triggers the release of siRNA into the cytoplasm following macropinocytosis[1].

分子量

2542.02

Formula

C112H189N41O25S
CAS 号
Sequence

Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Arg-Arg-Arg-His-Arg-Arg-His-Cys
Sequence Shortening

VLTTGLPALISWIRRRHRRHC
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

p5RHH 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

p5RHH1423724-82-6Othersendosomal acidificationhuman serum albumincanonical NFkB subunitsB16-GFP cellsnon-canonical NFkB subunitsadult T-cell leukemia/lymphomaB16-F10 melanoma cellsF8 murine ATLL cellsmacropinocytosisNFkB signalingInhibitorinhibitorinhibit

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目录号：
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