2. Membrane Transporter/Ion Channel
  3. EAAT
  4. Parawixin10

Parawixin10 (Compound 2) 是一种 N-酰基多胺。Parawixin10 在 EAAT1、EAAT2 或 EAAT3 放射性配体摄取实验中不能增强谷氨酸摄取。Parawixin10 在 EAAT1−EAAT3 放射性配体摄取实验中未表现出正变构调节活性，也无法以剂量依赖性且具有统计学显著性的方式提高小鼠的神经元存活率。Parawixin10 无神经保护活性。

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Parawixin10

Parawixin10 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

Parawixin10 相关抗体

Top Publications Citing Use of Products

查看 EAAT 亚型特异性产品:

查看所有亚型
EAAT1 EAAT2 EAAT3 EAAT4 EAAT5

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Parawixin10 (Compound 2) is an N-acylpolyamine. Parawixin10 fails to enhance glutamate uptake in radioligand uptake assays of EAAT1, EAAT2 or EAAT3. Parawixin10 exhibits no positive allosteric modulatory activity in radioligand uptake assays of EAAT1−EAAT3, nor can it improve neuronal survival rates in mice in a dose-dependent and statistically significant manner. Parawixin10 has no neuroprotective activity[1].

IC50 & Target[1][2][3]

EAAT1

 

EAAT2

 

EAAT3

 

体外研究
(In Vitro)

Parawixin10 (1 nM-10 μM; 10 min) 对表达 EAAT1、EAAT2 的 HEK293 细胞中 [3H]-D-Asp 或 [3H]-L-Glu 的摄取无调控作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Parawixin10 相关抗体:
分子量

843.63

Formula

C30H55I2N9O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Parawixin10 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Parawixin10Parawixin 10Parawixin-10EAATExcitatory amino acid transporter Glutamate transporter| C57BL/6J miceParawixia bistriataneuronal deathEAAT3HEK293 cellsprimary cortical mixed neuron-glia culturesglutamateEAAT1COS-7 cellsEAAT2Inhibitorinhibitorinhibit

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产品名称：
Parawixin10
目录号：
HY-182941
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