1. Protein Tyrosine Kinase/RTK
  2. VEGFR
  3. Peptide HRH

Peptide HRH 是一种可特异性结合 VEGF 受体的多肽。Peptide HRH 可抑制 VEGF 刺激的内皮细胞增殖。Peptide HRH 可抑制血管生成,并抑制角膜新生血管形成。Peptide HRH 可用于抗血管生成的相关研究。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

Peptide HRH

Peptide HRH Chemical Structure

CAS No. : 1228536-06-8

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Peptide HRH:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Peptide HRH is a polypeptide that specifically binds to VEGF receptors. Peptide HRH inhibits VEGF-stimulated endothelial cell proliferation. Peptide HRH inhibits angiogenesis and suppresses corneal neovascularization. Peptide HRH can be used in anti-angiogenesis related studies[1].

体外研究
(In Vitro)

Peptide HRH (0.95-3.85 μg/μL; 96 h) 可剂量依赖性地抑制 VEGF 刺激的人脐静脉内皮细胞 (HUVECs) 增殖[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: human umbilical vein endothelial cells (HUVECs) stimulated with VEGF
Concentration: 0.95; 1.9; 3.85 μg/μL
Incubation Time: 96 h
Result: Suppressed the proliferation of VEGF-stimulated HUVECs in a dose-dependent manner.
体内研究
(In Vivo)

Peptide HRH (10-50 μg/μL; local application to CAM; 48 h) 在鸡胚 CAM 模型中呈剂量依赖性抑制血管生成[1]
Peptide HRH (10 μg/μL;滴眼给药;每日 4 次;连续 14 天) 可显著抑制碱烧伤大鼠角膜模型中的角膜新生血管形成[1]
Peptide HRH (10 μg/μL;滴眼给药;每日 4 次;连续 14 天) 可显著抑制缝线诱导的大鼠角膜模型中的角膜新生血管形成[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley (male, alkali-burned corneal model)[1]
Dosage: 10 μg/μL
Administration: topical eye drops; four times per day; 14 days
Result: Significantly reduced corneal neovascularization area from days 3 to 14 post-burn.
Kept most of the corneal stroma free of blood vessels.
Animal Model: Sprague-Dawley (male, suture-induced corneal model)[1]
Dosage: 10 μg/μL
Administration: topical eye drops; four times per day; 14 days
Result: Significantly reduced maximum vessel length and total corneal neovascularization area from days 3 to 14 post-suture.
分子量

1521.69

Formula

C64H104N28O16

CAS 号
Sequence

His-Arg-His-Thr-Lys-Gln-Arg-His-Thr-Ala-Leu-His

Sequence Shortening

HRHTKQRHTALH

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Peptide HRH
目录号:
HY-P11775
需求量: