2. Others Neuronal Signaling Membrane Transporter/Ion Channel
  3. Isotope-Labeled Compounds iGluR
  4. Perfluoroenanthic acid-13C4

Perfluoroenanthic acid-13C4  (Synonyms: 全氟庚酸-13C4; Perfluoroheptanoic acid-13C4; Tridecafluoroheptanoic acid-13C4; PFHpA-13C4)

目录号: HY-21197S
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Perfluoroenanthic acid-13C4 (Perfluoroheptanoic acid-13C4) 是 13C 标记的 Perfluoroenanthic acid (HY-21197)。Perfluoroenanthic acid (Perfluoroheptanoic acid) 是一种全氟烷基物质 (PFAS)，妊娠期暴露会对子代小鼠精管发育和睾丸m6A RNA 甲基化产生不利影响，进而干扰精子发生，导致生殖毒性。Perfluoroenanthic acid 在初级皮层神经元培养中改变树突棘的形态发生和突触形成，增强神经活动和突触传递，升高兴奋性突触相关蛋白 Synaptophysin 和 PSD95 的表达。

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Perfluoroenanthic acid-<sup>13</sup>C<sub>4</sub>

Perfluoroenanthic acid-13C4 Chemical Structure

CAS No. : 2328024-55-9

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Other Forms of Perfluoroenanthic acid-13C4:

Perfluoroenanthic acid-13C4 相关抗体

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生物活性

Perfluoroenanthic acid-13C4 (Perfluoroheptanoic acid-13C4) is the 13C-labeled Perfluoroenanthic acid (HY-21197). Perfluoroenanthic acid (Perfluoroheptanoic acid) is a type of perfluoroalkyl substance (PFAS) that can negatively impact the development of seminiferous tubules and m6A RNA methylation in the testes of offspring mice when exposed during pregnancy, consequently disrupting spermatogenesis and leading to reproductive toxicity. Perfluoroenanthic acid alters the morphology of dendritic spines and synaptic formation in primary cortical neuron cultures, enhancing neuronal activity and synaptic transmission, and increasing the expression of excitatory synapse-related proteins Synaptophysin and PSD95[1][2].

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1. 该化合物可作为示踪剂。
2. 该化合物可作为 NMR、GC-MS 或 LC-MS 分析中的内标品，用于定量分析。
体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Perfluoroenanthic acid-13C4 相关抗体:
分子量

368.03

Formula

C313C4HF13O2
CAS 号
非标记 CAS
中文名称

全氟庚酸-13C4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Perfluoroenanthic acid-13C4 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Perfluoroenanthic acid-13C42328024-55-9Perfluoroheptanoic acid-13C4 Tridecafluoroheptanoic acid-13C4 PFHpA-13C4全氟庚酸-13C4Isotope-Labeled CompoundsiGluRIonotropic glutamate receptorsInhibitorinhibitorinhibit

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