2. PI3K/Akt/mTOR Apoptosis
  3. PI3K Akt Apoptosis
  4. PI3K/AKT-IN-5

PI3K/AKT-IN-5 (Compound 3h) 是一种 PI3K/AKT 抑制剂。PI3K/AKT-IN-5 表现出卓越的广谱抗癌活性，尤其对结直肠癌敏感。PI3K/AKT-IN-5 显著减少细胞集落形成、诱导 G2/M 期细胞周期阻滞和细胞凋亡 (apoptosis)。PI3K/AKT-IN-5 可用于研究结直肠癌。

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PI3K/AKT-IN-5

PI3K/AKT-IN-5 Chemical Structure

CAS No. : 3093148-10-5

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PI3K/AKT-IN-5 相关抗体

Top Publications Citing Use of Products

查看 PI3K 亚型特异性产品:

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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Akt Akt1 Akt2 Akt3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PI3K/AKT-IN-5 (Compound 3h) is a PI3K/AKT inhibitor. PI3K/AKT-IN-5 exhibits outstanding broad-spectrum anti-cancer activity, especially being sensitive to colorectal cancer. PI3K/AKT-IN-5 significantly reduces cell colony formation, induces G2/M phase cell cycle arrest and cell apoptosis. PI3K/AKT-IN-5 can be used for research on colorectal cancer[1].

分子量

404.48

Formula

C23H20N2O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PI3K/AKT-IN-5 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PI3K/AKT-IN-53093148-10-5PI3KAktApoptosisPhosphoinositide 3-kinasePKBProtein kinase BColorectal cancerPI3K-AKTIndoleIndolineIndolin-2-imineInhibitorinhibitorinhibit

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