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  4. Poly diallyldimethylammonium chloride

Poly diallyldimethylammonium chloride 是一种带有季铵侧基的阳离子抗菌聚合物，同时具有杀微生物活性。Poly diallyldimethylammonium chloride 可用于细菌和真菌感染 (大肠杆菌、金黄色葡萄球菌、白色念珠菌感染) 的研究。

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Poly diallyldimethylammonium chloride

Poly diallyldimethylammonium chloride Chemical Structure

CAS No. : 26062-79-3

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Poly diallyldimethylammonium chloride 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Poly diallyldimethylammonium chloride is a cationic antimicrobial polymer with quaternary ammonium side chains, and it exhibits microbicidal activity. Poly diallyldimethylammonium (chloride) can be used in studies of bacterial and fungal infections (E. coli, S. aureus, C. albicans infections)[1].

体外研究
(In Vitro)

Poly diallyldimethylammonium (chloride) (用于纳米颗粒合成的浓度为 3-5 mg/mL；对应制剂 A3、A4、A5、B3、B4、B5 中最终掺入的 PDDA 浓度为 1.53-3.24 mg/mL)- 负载该物质的 PMMA/PDDA 纳米颗粒具有良好的长期胶体稳定性，其 zeta 平均粒径为 230-328 nm，zeta 电位为 62-69 mV，且多分散性较低；此外，其外层 PDDA 层在高离子强度条件下会发生塌陷[1]。
Free Poly diallyldimethylammonium (chloride) (0.003-1.5 mg/mL; 1 hour) 可强效杀灭 Escherichia coli ATCC 25322 和 Candida albicans ATCC 90028，其 MMC 为 0.005 mg/mL，对 Staphylococcus aureus ATCC 29213 的活性较弱 (MMC >0.5 mg/mL)；而与游离 PDDA 相比，PMMA/PDDA NPs 对 S. aureus 和 C. albicans 的抗菌活性降低，且溶血毒性增强[1]。
Free Poly diallyldimethylammonium (chloride) (0.003-1.5 mg/mL; 1 hour) 在可杀死大肠杆菌 ATCC 25322 和白色念珠菌 ATCC 90028 的浓度下不会引发溶血，而 PMMA/PDDA NPs 在对金黄色葡萄球菌 ATCC 29213 和白色念珠菌 ATCC 90028 有效的浓度下会诱导显著溶血[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Poly diallyldimethylammonium chloride 相关抗体:
Formula

(C8H16N.Cl)x
CAS 号
性状

粘稠液体

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Store at room temperature, keep dry and cool

In solvent -80°C 1 year
-20°C 6 months
纯度 & 产品资料
参考文献

Poly diallyldimethylammonium chloride 相关分类

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Keywords:

Poly diallyldimethylammonium26062-79-3BacterialEscherichia coliCandida albicans ATCC 90028Candida albicansStaphylococcus aureuspoly(methylmethacrylate) nanoparticlesfungal infectionsEscherichia coli ATCC 25322microbial cell membranemicrobial cell wallbacterial infectionsInhibitorinhibitorinhibit

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