2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. Ponometrep

Ponometrep (BHV-2100) 是一种瞬时受体电位 M 型 3 通道 (TRPM3) 拮抗剂，其 IC50 值为 1-10 nM。Ponometrep 具有镇痛活性，可用于神经系统疾病的研究。

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Ponometrep

Ponometrep Chemical Structure

CAS No. : 2776175-74-5

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规格 价格 是否有货
5 mg ￥1800
询问价格 & 货期
10 mg ￥2925
询问价格 & 货期
25 mg ￥5850
询问价格 & 货期
50 mg 询价 询问价格 & 货期
100 mg 询价 询问价格 & 货期

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Customer Review

Ponometrep 相关抗体

Top Publications Citing Use of Products

查看 TRP Channel 亚型特异性产品:

查看所有亚型
TRPA1 TRPC3 TRPC4 TRPC5 TRPM8 TRPM2 TRPM3 TRPM4 TRPML1 TRPML2 TRPML3 TRPV1 TRPV2 TRPV3 TRPV4 TRPV6

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ponometrep (BHV-2100) is a transient receptor potential melastatin 3 (TRPM3) antagonist with IC50 values of 1-10 nM. Ponometrep shows analgesic activity and can be used for the research of neurological diseases[1].

IC50 & Target[1]

TRPM3

1-10 nM (IC50)

体外研究
(In Vitro)

BHV-2100 可抑制人、小鼠和大鼠的 TRPM3，其 IC50 值为 1-10 nM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Ponometrep 相关抗体:
体内研究
(In Vivo)

BHV-2100 可抑制小鼠和大鼠中由 PS 诱发的疼痛反应，其 ED50 分别为 1.3 mg/kg 和 2.5 mg/kg[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

389.43

Formula

C18H19N3O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ponometrep 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ponometrep2776175-74-5BHV-2100BHV2100BHV 2100TRP ChannelTransient receptor potential channelsmouse modelTRPM3migraine painpregnenolone sulfateion channelsInhibitorinhibitorinhibit

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产品名称：
Ponometrep
目录号：
HY-182466
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