2. Others GPCR/G Protein MAPK/ERK Pathway Stem Cell/Wnt PI3K/Akt/mTOR
  3. Drug Derivative Prostaglandin Receptor ERK Akt JNK p38 MAPK
  4. rel-Latanoprost acid

rel-Latanoprost acid 是 Latanoprost acid (HY-113756A) 的一种相对构型。Latanoprost acid 是前列腺素 (PG) F2α 的类似物，是选择性的前列腺素受体 FP 激动剂，FP 可以特异性激活 FP-PG 受体。Latanoprost acid 通过抑制 ERK，AKT，JNK 和 p38 级联反应，继而沿 c-fos/NFATc1 通路抑制 RANKL 诱导的破骨细胞生成和功能。Latanoprost acid 是一种可降低眼内压力的活性分子。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

rel-Latanoprost acid

rel-Latanoprost acid Chemical Structure

CAS No. : 2699713-95-4

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of rel-Latanoprost acid:

rel-Latanoprost acid 相关抗体

Top Publications Citing Use of Products

查看 Prostaglandin Receptor 亚型特异性产品:

查看所有亚型
DP EP FP IP TXA2/TP TXB2

查看 ERK 亚型特异性产品:

查看所有亚型
ERK ERK1 ERK2 ERK5 ERK8

查看 Akt 亚型特异性产品:

查看所有亚型
Akt Akt1 Akt2 Akt3

查看 JNK 亚型特异性产品:

查看所有亚型
JNK1 JNK2 JNK3 JNK

查看 p38 MAPK 亚型特异性产品:

查看所有亚型
p38 MAPK Akt1 p38α p38β MAPK13 p38δ p38γ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

rel-Latanoprost acid is a relative configuration of Latanoprost acid (HY-113756A). Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor[1]. Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes[1][2].

IC50 & Target[1]

FP

 

体外研究
(In Vitro)

Latanoprost acid (10-20 μM;24 h) 可降低 c-fos 和 NFATc1 的蛋白表达[1]。
Latanoprost acid (10μM with 50ng/ml RANKL) 能显著抑制 ERK、p38、AKT 和 JNK[1]。
Latanoprost acid (10-20 μM) 可显著抑制成熟破骨细胞的形成[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

rel-Latanoprost acid 相关抗体:
体内研究
(In Vivo)

Latanoprost acid (20 mg/kg；腹腔注射；每天一次，连续 7 天) 显著阻止了 LPS (HY-D1056) 诱导的骨破坏[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

390.51

Formula

C23H34O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

rel-Latanoprost acid 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

rel-Latanoprost acid2699713-95-4Drug DerivativeProstaglandin ReceptorERKAktJNKp38 MAPKDrug derivativeExtracellular signal regulated kinasesPKBProtein kinase Bc-Jun N-terminal kinaseInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
rel-Latanoprost acid
目录号：
HY-113756B
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z