1. 疾病领域
  2. 血液和心脑血管疾病
  3. [Rh(cod)Cl]2

[Rh(cod)Cl]2  (Synonyms: Chloro(1,5-cyclooctadiene)rhodium(I) dimer)

目录号: HY-Y1094
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含量: 98.2%
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[Rh(cod)Cl]2 (Chloro(1,5-cyclooctadiene)rhodium(I) dimer) 是一种铑 (I) 有机金属二聚体配合物。[Rh(cod)Cl]2 能够抑制血小板活化因子介导的血小板聚集,在洗涤过的兔血小板和人富血小板血浆中的 IC50 值分别为 5.2 和 43.3 μM。[Rh(cod)Cl]2 还可以抑制凝血酶、ADP (HY-W010918) 和胶原蛋白诱导的聚集,其 IC50 值分别为 16.7, 162 和 69.8 μM。[Rh(cod)Cl]2 可用于心血管疾病的研究,如血栓。

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[Rh(cod)Cl]2

[Rh(cod)Cl]2 Chemical Structure

CAS No. : 12092-47-6

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  • 生物活性

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生物活性

[Rh(cod)Cl]2 (Chloro(1,5-cyclooctadiene)rhodium(I) dimer) is a rhodium (I) organometallic dimer complex. [Rh(cod)Cl]2 can inhibit platelet-activating factor-mediated platelet aggregation with IC50 values of 5.2 and 43.3 μM in washed rabbit platelets and human platelet-rich plasmas. [Rh(cod)Cl]2 also can inhibit thrombin-, ADP (HY-W010918)- and collagen-induced aggregation with IC50 values of 16.7, 162 and 69.8 μM. [Rh(cod)Cl]2 can be used for the research of cardiovascular disease, such as thrombosis[1].

分子量

493.08

Formula

C16H24Cl2Rh2

CAS 号
性状

固体

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

纯度 & 产品资料

纯度: 98.2%

参考文献
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