1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. RWJ 29009

RWJ 29009 是一种高选择性 ATP 敏感性钾通道 (potassium channel) 激动剂。RWJ 29009 激活血管平滑肌细胞膜上的钾通道,促进钾离子外流导致细胞膜超极化,从而引发冠状动脉及外周血管舒张。RWJ 29009 有望用于心血管疾病的研究,如急性心肌缺血和高血压。

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RWJ 29009

RWJ 29009 Chemical Structure

CAS No. : 143164-10-7

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生物活性

RWJ 29009 is a highly selective ATP-sensitive potassium channel agonist. RWJ 29009 activates potassium channel in vascular smooth muscle cells, promoting potassium efflux and membrane hyperpolarization to induce coronary and peripheral vasodilation. RWJ 29009 is promising for research of cardiovascular diseases such as acute myocardial ischemia and hypertension[1].

分子量

326.37

Formula

C14H18N2O5S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
RWJ 29009
目录号:
HY-120554
需求量: