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  3. Drug Intermediate
  4. (S)-Ponesimod

(S)-Ponesimod 是一种药物杂质。

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(S)-Ponesimod

(S)-Ponesimod Chemical Structure

CAS No. : 854111-49-2

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规格 价格 是否有货 数量
5 mg ￥425
In-stock
10 mg ￥722
In-stock
25 mg ￥1530
In-stock
50 mg ￥2550
In-stock
100 mg ￥4250
In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Other Forms of (S)-Ponesimod:

(S)-Ponesimod 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

(S)-Ponesimod is a drug impurity.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
CHO EC50
1108 nM
Compound: 8bo, ACT-128800
Agonist activity at human recombinant S1P4 receptor expressed in CHO cells by GTPgammaS binding assay
Agonist activity at human recombinant S1P4 receptor expressed in CHO cells by GTPgammaS binding assay
[PMID: 20446681]
CHO EC50
123 nM
Compound: 8bo, ACT-128800
Agonist activity at human recombinant S1P3 receptor expressed in CHO cells by GTPgammaS binding assay
Agonist activity at human recombinant S1P3 receptor expressed in CHO cells by GTPgammaS binding assay
[PMID: 20446681]
CHO EC50
59.1 nM
Compound: 8bo, ACT-128800
Agonist activity at human recombinant S1P5 receptor expressed in CHO cells by GTPgammaS binding assay
Agonist activity at human recombinant S1P5 receptor expressed in CHO cells by GTPgammaS binding assay
[PMID: 20446681]
CHO EC50
9.1 nM
Compound: 8bo, ACT-128800
Agonist activity at human recombinant S1P1 receptor expressed in CHO cells by GTPgammaS binding assay
Agonist activity at human recombinant S1P1 receptor expressed in CHO cells by GTPgammaS binding assay
[PMID: 20446681]
CHO IC50
142 nM
Compound: 8bo, ACT-128800
Displacement of [33P]S1P from human recombinant S1P5 receptor expressed in CHO cells by scintillation counting
Displacement of [33P]S1P from human recombinant S1P5 receptor expressed in CHO cells by scintillation counting
[PMID: 20446681]
CHO IC50
1956 nM
Compound: 8bo, ACT-128800
Displacement of [33P]S1P from human recombinant S1P4 receptor expressed in CHO cells by scintillation counting
Displacement of [33P]S1P from human recombinant S1P4 receptor expressed in CHO cells by scintillation counting
[PMID: 20446681]
HEK293 EC50
105 nM
Compound: 8bo, ACT-128800
Agonist activity at human recombinant S1P3 receptor expressed in HEK cells by GTPgammaS binding assay
Agonist activity at human recombinant S1P3 receptor expressed in HEK cells by GTPgammaS binding assay
[PMID: 20446681]
HEK293 EC50
5.7 nM
Compound: 8bo, ACT-128800
Agonist activity at human recombinant S1P1 receptor expressed in HEK cells by GTPgammaS binding assay
Agonist activity at human recombinant S1P1 receptor expressed in HEK cells by GTPgammaS binding assay
[PMID: 20446681]
HEK293 EC50
> 10000 nM
Compound: 8bo, ACT-128800
Agonist activity at human recombinant S1P2 receptor expressed in HEK cells by GTPgammaS binding assay
Agonist activity at human recombinant S1P2 receptor expressed in HEK cells by GTPgammaS binding assay
[PMID: 20446681]
HEK293 IC50
2068 nM
Compound: 8bo, ACT-128800
Displacement of [33P]S1P from human recombinant S1P3 receptor expressed in HEK cells by scintillation counting
Displacement of [33P]S1P from human recombinant S1P3 receptor expressed in HEK cells by scintillation counting
[PMID: 20446681]
HEK293 IC50
6 nM
Compound: 8bo, ACT-128800
Displacement of [33P]S1P from human recombinant S1P1 receptor expressed in HEK cells by scintillation counting
Displacement of [33P]S1P from human recombinant S1P1 receptor expressed in HEK cells by scintillation counting
[PMID: 20446681]
HEK293 IC50
> 10000 nM
Compound: 8bo, ACT-128800
Displacement of [33P]S1P from human recombinant S1P2 receptor expressed in HEK cells by scintillation counting
Displacement of [33P]S1P from human recombinant S1P2 receptor expressed in HEK cells by scintillation counting
[PMID: 20446681]
分子量

460.97

Formula

C23H25ClN2O4S
CAS 号
性状

固体

颜色

Off-white to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

(S)-Ponesimod 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-Ponesimod854111-49-2Drug IntermediateDrug IintermediateInhibitorinhibitorinhibit

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目录号：
HY-Z0676
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