2. 多肽产品
  3. 多肽及其衍生物
  4. scHAP-1

scHAP-1 是一种乱序 HAP-1 肽，可特异性结合人和兔的成纤维细胞样滑膜细胞，与人脐静脉内皮细胞的结合作用极弱。scHAP-1L 能够高效、特异性地在体内富集于炎症关节，可作为靶头连接到载药脂质体上，能显著提高药物在炎症关节的靶向递送效率，从而增强抗炎疗效，并延长药物作用时间。scHAP-1 可用于类风湿性关节炎的相关研究[1]。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

scHAP-1

scHAP-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of scHAP-1:

scHAP-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

scHAP-1 is a disordered HAP-1 peptide that specifically binds to human and rabbit fibroblast-like synoviocytes, but shows extremely weak binding to human umbilical vein endothelial cells. scHAP-1L can efficiently and specifically accumulate in inflamed joints in vivo. scHAP-1 significantly improves the targeted delivery efficiency of drugs to inflamed joints when conjugated as a targeting ligand to drug-loaded liposomes, thereby enhancing anti-inflammatory efficacy and prolonging the duration of drug action. scHAP-1 is applicable to studies related to rheumatoid arthritis[1].

体内研究
(In Vivo)
Animal Model: Wistar rats (female; adjuvant-induced arthritis model)[1]
Dosage: 0.5 mg drug/0.5 ml/250 g rat/day
Administration: i.v.; two consecutive days
Result: Showed a 9-fold increase in fluorescence signal in arthritic joints compared to unaffected joints in the same animals at 3 hours post-injection.
分子量

1335.47

Formula

C60H90N18O17
Sequence

Ala-Leu-Ser-Gln-Ala-Phe-Arg-His-Ala-Phe-Thr-Ser
Sequence Shortening

ALSQAFRHAFTS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

scHAP-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

scHAP-1scHAP1scHAP 1OthersHUVECsTNF-αinflamed rat adjuvant-induced arthritis jointsrheumatoid arthritishuman fibroblast-like synovial cellshFLSrabbit fibroblast-like synovial cellsadjuvant-induced arthritisrFLShuman umbilical vein endothelial cellsInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
scHAP-1
目录号：
HY-P4096B
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z