2. Anti-infection
  3. HIV HBV
  4. Schinlignan B

Schinlignan B (Angeloylgomisin P) 是一种木脂素，具有抗氧化、抗 HIV、抗 HBV 活性，发现于 Schisandra 属植物中。Schinlignan B 有望用于抗氧化相关疾病的研究。

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Schinlignan B

Schinlignan B Chemical Structure

CAS No. : 77881-08-4

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Schinlignan B 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Schinlignan B (Angeloylgomisin P) is a lignan with antioxidant, anti-HIV, anti-HBV activities, which is found in plants of the Schisandra genus. Schinlignan B is promising for research of antioxidant-associated diseases[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
55.1 μM
Compound: Gomisin B
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
DU-145 IC50
64.7 μM
Compound: Gomisin B
Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
HEK293 IC50
52 μM
Compound: Gomisin B
Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
IMR-32 IC50
66.8 μM
Compound: Gomisin B
Cytotoxicity against human IMR32 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human IMR32 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
MDA-MB-231 IC50
60.5 μM
Compound: Gomisin B
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
PANC-1 IC50
53.6 μM
Compound: Gomisin B
Cytotoxicity against human PANC1 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human PANC1 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
SiHa IC50
51.2 μM
Compound: Gomisin B
Cytotoxicity against human SiHa cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
Cytotoxicity against human SiHa cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
[PMID: 28818768]
分子量

514.56

Formula

C28H34O9
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Schinlignan B 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Schinlignan B77881-08-4Angeloylgomisin PHIVHBVHuman immunodeficiency virusHepatitis B virusantioxidantanti-HIVanti-HBV activitiesantioxidant-associated diseasesInhibitorinhibitorinhibit

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