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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

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Mouse thymus cells

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By Targets:	Autophagy (1) Endogenous Metabolite (3) Isotope-Labeled Compounds (1) Reference Standards (1)
By Research Areas:	Cancer (4)
Oligonucleotides:	鸟苷 (1) 核苷类似物 (1)

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Targets Recommended: Nuclear Factor of activated T Cells (NFAT) TREM receptor

Cat. No.	Product Name	Target	Research Area	Chemical Structure

HY-17563

2'-Deoxyguanosine 5 篇以上引用文献 Deoxyguanosine; Guanine deoxyriboside	Endogenous Metabolite	Cancer
2′-脱氧鸟苷 2’-Deoxyguanosine (Deoxyguanosine) 是一种具有多种生物活性的嘌呤核苷。2’-Deoxyguanosine 可诱导小鼠胸腺细胞 DNA 分裂。2’-Deoxyguanosine 是植物细胞中有效的细胞分裂抑制剂。

HY-17563R

2'-Deoxyguanosine (Standard) Deoxyguanosine (Standard); Guanine deoxyriboside (Standard)	Reference Standards Endogenous Metabolite	Cancer
2′-脱氧鸟苷 (标准品) 2'-Deoxyguanosine (Standard) 是 2'-Deoxyguanosine 的分析标准品。本产品用于研究及分析应用。2’-Deoxyguanosine (Deoxyguanosine) 是一种具有多种生物活性的嘌呤核苷。2’-Deoxyguanosine 可诱导小鼠胸腺细胞 DNA 分裂。2’-Deoxyguanosine 是植物细胞中有效的细胞分裂抑制剂。

HY-17563S

2'-Deoxyguanosine-13C,15N2 Deoxyguanosine-¹³C,¹⁵N₂; Guanine deoxyriboside-¹³C,¹⁵N₂	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
2'-Deoxyguanosine-¹³C,¹⁵N₂ (Deoxyguanosine-¹³C,¹⁵N₂; Guanine deoxyriboside-¹³C,¹⁵N₂) 是 ¹³C 和 ¹⁵N 标记的 2'-Deoxyguanosine (HY-17563)。2’-Deoxyguanosine (Deoxyguanosine) 是一种具有多种生物活性的嘌呤核苷。2’-Deoxyguanosine 可诱导小鼠胸腺细胞 DNA 分裂。2’-Deoxyguanosine 是植物细胞中有效的细胞分裂抑制剂。

HY-P992056

Anti-Human/Mouse LY6E Antibody (9B12)	Autophagy	Cancer
Anti-Human/Mouse LY6E Antibody (9B12) 是一种高亲和力的多靶点抗体，可靶向结合 LY6E。Anti-Human/Mouse LY6E Antibody (9B12) 能够特异性结合细胞表面的 LY6E 并经由依赖脂筏的内吞作用进入溶酶体，从而在体外及体内模型中有效抑制表达 LY6E 的多种实体瘤 (如乳腺癌、肺癌等) 的生长。Anti-Human/Mouse LY6E Antibody (9B12) 表现出双重机制：一方面，Anti-Human/Mouse LY6E Antibody (9B12) 通过阻断 PILRα 与 CD8α 的相互作用，特异性降低外周 CD8⁺ T 细胞存活率并诱导其活化，打破细胞静息状态；另一方面，Anti-Human/Mouse LY6E Antibody (9B12) 还能在非变性和变性条件下识别并免疫沉淀 IDE，用于研究 IDE 的亚细胞定位及蛋白相互作用。Anti-Human/Mouse LY6E Antibody (9B12) 对 CD8⁺ T 细胞的调节作用严格依赖于 PILRα 的存在，且不影响 CD4⁺ T 细胞或胸腺内的 T 细胞发育，显示出高度的特异性。

Cat. No.	Product Name	Target	Research Area	图片

HY-P992056

Anti-Human/Mouse LY6E Antibody (9B12)	Autophagy	Cancer
Anti-Human/Mouse LY6E Antibody (9B12) 是一种高亲和力的多靶点抗体，可靶向结合 LY6E。Anti-Human/Mouse LY6E Antibody (9B12) 能够特异性结合细胞表面的 LY6E 并经由依赖脂筏的内吞作用进入溶酶体，从而在体外及体内模型中有效抑制表达 LY6E 的多种实体瘤 (如乳腺癌、肺癌等) 的生长。Anti-Human/Mouse LY6E Antibody (9B12) 表现出双重机制：一方面，Anti-Human/Mouse LY6E Antibody (9B12) 通过阻断 PILRα 与 CD8α 的相互作用，特异性降低外周 CD8⁺ T 细胞存活率并诱导其活化，打破细胞静息状态；另一方面，Anti-Human/Mouse LY6E Antibody (9B12) 还能在非变性和变性条件下识别并免疫沉淀 IDE，用于研究 IDE 的亚细胞定位及蛋白相互作用。Anti-Human/Mouse LY6E Antibody (9B12) 对 CD8⁺ T 细胞的调节作用严格依赖于 PILRα 的存在，且不影响 CD4⁺ T 细胞或胸腺内的 T 细胞发育，显示出高度的特异性。

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-17563R

2'-Deoxyguanosine (Standard) Deoxyguanosine (Standard); Guanine deoxyriboside (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Immune System Disorder Disease markers Endocrine diseases Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
2′-脱氧鸟苷 (标准品) 2'-Deoxyguanosine (Standard) 是 2'-Deoxyguanosine 的分析标准品。本产品用于研究及分析应用。2’-Deoxyguanosine (Deoxyguanosine) 是一种具有多种生物活性的嘌呤核苷。2’-Deoxyguanosine 可诱导小鼠胸腺细胞 DNA 分裂。2’-Deoxyguanosine 是植物细胞中有效的细胞分裂抑制剂。

Cat. No.	Product Name	Chemical Structure

HY-17563S

2'-Deoxyguanosine-13C,15N2
2'-Deoxyguanosine-¹³C,¹⁵N₂ (Deoxyguanosine-¹³C,¹⁵N₂; Guanine deoxyriboside-¹³C,¹⁵N₂) 是 ¹³C 和 ¹⁵N 标记的 2'-Deoxyguanosine (HY-17563)。2’-Deoxyguanosine (Deoxyguanosine) 是一种具有多种生物活性的嘌呤核苷。2’-Deoxyguanosine 可诱导小鼠胸腺细胞 DNA 分裂。2’-Deoxyguanosine 是植物细胞中有效的细胞分裂抑制剂。

Cat. No.	Product Name		Classification

HY-17563

2'-Deoxyguanosine 5 篇以上引用文献 Deoxyguanosine; Guanine deoxyriboside		核苷类似物鸟苷
2’-Deoxyguanosine (Deoxyguanosine) 是一种具有多种生物活性的嘌呤核苷。2’-Deoxyguanosine 可诱导小鼠胸腺细胞 DNA 分裂。2’-Deoxyguanosine 是植物细胞中有效的细胞分裂抑制剂。

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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