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ventral prostate

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By Targets:	5 alpha Reductase (1) Androgen Receptor (6) Progesterone Receptor (2) Reference Standards (1)
By Research Areas:	Cancer (2) Endocrinology (4) Metabolic Disease (1)

抑制剂 & 激动剂

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重组蛋白

抗体

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Targets Recommended: PSMA

Cat. No.	Product Name	Target	Research Area	Chemical Structure

HY-17375

Allylestrenol 1 篇文献验证	Progesterone Receptor Androgen Receptor	Endocrinology
烯丙雌醇 Allylestrenol 是一种口服有效的合成抗雄激素 (androgen) 性类固醇。Allylestrenol 可在体内预防流产。Allylestrenol 显著影响大鼠模型中的睾酮孕酮水平。Allylestrenol 可减轻大鼠模型中的腹侧前列腺重量。

HY-N13195

(15α)-15,26-Dihydroxylanosta-7,9(11),24-trien-3-one	5 alpha Reductase	Others
(15α)-15,26-Dihydroxylanosta-7,9(11),24-trien-3-one 显示出 5α-还原酶 (5a-reductase) 抑制活性，其 IC₅₀ 值为 41.9 μM。(15α)-15,26-Dihydroxylanosta-7,9(11),24-trien-3-one 抑制了由睾酮诱导的大鼠腹侧前列腺的生长。(15α)-15,26-Dihydroxylanosta-7,9(11),24-trien-3-one 有望用于良性前列腺增生 (BPH) 以及其他与 5α-二氢睾酮 (DHT) 相关疾病的研究，如痤疮和男性型脱发。

HY-17375R

Allylestrenol (Standard)	Progesterone Receptor Reference Standards Androgen Receptor	Endocrinology
烯丙雌醇 (标准品) Allylestrenol (Standard)是 Allylestrenol 的分析标准品。本产品用于研究及分析应用。Allylestrenol 是一种口服有效的合成抗雄激素 (androgen) 性类固醇。Allylestrenol 可在体内预防流产。Allylestrenol 显著影响大鼠模型中的睾酮孕酮水平。Allylestrenol 可减轻大鼠模型中的腹侧前列腺重量。

HY-116219

WB2838	Androgen Receptor	Endocrinology Cancer
WB2838 是一种非甾体雄激素受体 (androgen-receptor) 拮抗剂 (对部分纯化的鼠前列腺胞浆受体的 IC₅₀ 为 0.8 μM)。WB2838 对雄激素反应性乳腺癌具有抗癌活性。WB2838 还对 Testosterone propionate 诱导的腹侧前列腺生长具有抑制作用。

HY-180409

YM580	Androgen Receptor	Cancer
YM580 是一种强效、口服有效且选择性高的雄激素受体 (AR) 拮抗剂 (IC₅₀ = 0.11 μM，hAR Ki = 4.6 nM，rAR Ki = 6.2 nM)。YM580 对 PR、GR 和 ERα 具有良好的选择性 (K_i > 3300 nM)。YM580 在成年完整大鼠中呈剂量依赖性地降低腹侧前列腺重量，且不影响血清睾酮水平。YM580 可用于前列腺癌的研究。

HY-119436

LG-120907	Androgen Receptor	Metabolic Disease
LG-120907 是一种选择性雄激素受体 (AR) 拮抗剂，K_i 值为 26 nM。LG-120907 可抑制体内睾酮诱导的腹侧前列腺 (VP) 组织重量和精囊 (SV) 组织重量的增加。

HY-180410

YM-1758735	Androgen Receptor	Endocrinology
YM-1758735 是一种具有口服活性的雄激素受体 (AR) 拮抗剂，其 IC₅₀为 0.2 μM。YM-1758735 可抑制 AR 介导的转录激活。YM-1758735 可用于前列腺的相关研究。

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N13195

(15α)-15,26-Dihydroxylanosta-7,9(11),24-trien-3-one	Triterpenes Microorganisms Terpenoids Source Classification	5 alpha Reductase
(15α)-15,26-Dihydroxylanosta-7,9(11),24-trien-3-one 显示出 5α-还原酶 (5a-reductase) 抑制活性，其 IC₅₀ 值为 41.9 μM。(15α)-15,26-Dihydroxylanosta-7,9(11),24-trien-3-one 抑制了由睾酮诱导的大鼠腹侧前列腺的生长。(15α)-15,26-Dihydroxylanosta-7,9(11),24-trien-3-one 有望用于良性前列腺增生 (BPH) 以及其他与 5α-二氢睾酮 (DHT) 相关疾病的研究，如痤疮和男性型脱发。

Species:	Human (3)
Tag:	His (2) Tag Free (1) B2M (1)
Source:	HEK293 (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	图片

HY-P72146

	Claudin-3/CLDN3 Protein, Human (His-B2M) C7orf1; Claudin-3; Claudin3; CLD3_HUMAN; CLDN 3; Cldn3; Clostridium perfringens enterotoxin receptor 2; CPE R2; CPE receptor 2; CPE-R 2; CPE-receptor 2; CPETR 2; CPETR2; HRVP 1; HRVP1; Rat ventral prostate 1 like protein; Rat ventral prostate.1 protein homolog; RVP1; ventral prostate.1 like protein; ventral prostate.1 protein homolog	Human	E. coli
	Claudin-3 蛋白/CLDN3 蛋白 Claudin-3/CLDN3 蛋白在紧密连接中发挥着关键作用，通过不依赖钙的细胞粘附活性消除细胞间隙。它通过与其他 CLDN 成员（包括 CLDN1 和 CLDN2）形成均聚物和杂聚物而表现出多功能性。Claudin-3/CLDN3 Protein, Human (His-B2M) 是重组的 Claudin-3/CLDN3 蛋白，由 E. coli 表达，带有 N-6*His, B2M 标签。

HY-P700472

	Claudin-3/CLDN3 Protein-VLP, Human (HEK293, His) C7orf1; Claudin-3; Claudin3; CLD3_HUMAN; CLDN 3; Cldn3; Clostridium perfringens enterotoxin receptor 2; CPE R2; CPE receptor 2; CPE-R 2; CPE-receptor 2; CPETR 2; CPETR2; HRVP 1; HRVP1; Rat ventral prostate 1 like protein; Rat ventral prostate.1 protein homolog; RVP1; ventral prostate.1 like protein; ventral prostate.1 protein homolog	Human	HEK293
	Claudin-3 蛋白/CLDN3 蛋白-病毒样颗粒 Claudin-3/CLDN3 Protein-VLP, Human (HEK293, His)推荐用于免疫动物、ELISA。不推荐应用于受配体互作实验和SPR/BLI分析, 因为VLP包膜上还有宿主其他无关膜蛋白, 受配体互作会有很强的背景干扰。 SPR/BLI分析则对芯片和实验方案有较高要求，成功率较低。如果需要VLP对照，推荐HY-P701236。标签只能在变性条件下检测到。

HY-P704506

	Claudin-3/CLDN3 Protein-VLP, Human (HEK293) C7orf1; Claudin-3; Claudin3; CLD3_HUMAN; CLDN 3; Cldn3; Clostridium perfringens enterotoxin receptor 2; CPE R2; CPE receptor 2; CPE-R 2; CPE-receptor 2; CPETR 2; CPETR2; HRVP 1; HRVP1; Rat ventral prostate 1 like protein; Rat ventral prostate.1 protein homolog; RVP1; ventral prostate.1 like protein; ventral prostate.1 protein homolog	Human	HEK293
	Claudin-3/CLDN3 Protein-VLP, Human (HEK293)推荐用于免疫动物、ELISA。不推荐应用于受配体互作实验和SPR/BLI分析, 因为VLP包膜上还有宿主其他无关膜蛋白, 受配体互作会有很强的背景干扰。 SPR/BLI分析则对芯片和实验方案有较高要求，成功率较低。如果需要VLP对照，推荐HY-P705433。

产品对比


产品	In-stock - + Add to Cart
货号
种属
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标签
蛋白编号
基因 ID
分子量
纯度
内毒素含量
生物活性
性状
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运输条件
Free Sample	Yes No
规格	*该产品已“停产”。等效替代： / In-stock - + Add to Cart 询价

Cat. No.	Compare	Product Name	Application	Reactivity	图片

HY-P86091

	Claudin 3 Antibody (YA5783) C7orf1; Claudin-3; Claudin3; CLD3_HUMAN; CLDN 3; Cldn3; Clostridium perfringens enterotoxin receptor 2; CPE R2; CPE receptor 2; CPE-R 2; CPE-receptor 2; CPETR 2; CPETR2; HRVP 1; HRVP1; Rat ventral prostate 1 like protein; Rat ventral prostate.1 protein homolog; RVP1; ventral prostate.1 like protein; ventral prostate.1 protein homolog	WB, IHC-P, IP, ELISA, IF-Tissue	Human, Mouse, Rat
	Claudin 3 Antibody (YA5783) 是一个兔来源、无偶联标记、抗 Claudin 3 的 IgG 单克隆抗体。

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规格	*该产品已“停产”。等效替代： / In-stock - + Add to Cart 询价

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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