2. Others Membrane Transporter/Ion Channel Neuronal Signaling
  3. Reference Standards nAChR
  4. SEN12333 (Standard)

SEN12333 (Standard) 是 SEN12333 (HY-107678) 的分析标准品。本产品用于研究及分析应用。SEN 12333 是一种强效、选择性和口服活性的 α7 nAChR 激动剂。SEN12333 对 GH4C1 细胞中表达的大鼠 α7 nAChRs 具有很高的亲和性 (K>i=260 nM)，并在功能性 Ca2+ 通量研究 (EC50=1.6 μM) 中起到完全激动剂的作用。SEN 12333 可以用于 AD 和精神分裂症研究。

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SEN12333 (Standard)

SEN12333 (Standard) Chemical Structure

CAS No. : 874450-44-9

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SEN12333 (Standard) 相关抗体

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生物活性

SEN12333 (Standard) is the analytical standard of SEN12333 (HY-107678). This product is intended for research and analytical applications. SEN 12333 (WAY-317538) is a potent, selective and orally active α7 nAChR agonist. SEN12333 displays high affinity for the rat α7 nAChRs expressed in GH4C1 cells (K>i=260 nM) and acts as full agonist in functional Ca2+ flux studies (EC50=1.6 μM). SEN 12333 is used for AD and schizophrenia research[1].

分子量

339.43

Formula

C20H25N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SEN12333 (Standard) 相关分类

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Keywords:

SEN12333 (Standard)874450-44-9Reference StandardsnAChRNicotinic acetylcholine receptorsNeuroprotectiveschizophreniaADAlzheimer's DiseaseInhibitorinhibitorinhibit

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