2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. SMCC

SMCC (GMP) 是 SMCC (HY-42360) 的 GMP 级别。GMP 指南用于生产 SMCC (HY-42360) (GMP)。GMP 小分子可作为细胞研究生产的辅助试剂。SMCC (GMP) 是一种蛋白质交联剂。SMCC (GMP) 含有一个胺反应性 N-羟基琥珀酰亚胺酯基团和一个巯基反应性马来酰亚胺基团，可用于蛋白质的偶联。SMCC 偶联抗原可诱导脾细胞产生抗原特异性免疫应答。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SMCC

SMCC Chemical Structure

CAS No. : 64987-85-5

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SMCC 相关抗体

Top Publications Citing Use of Products

查看 ADC Linker 亚型特异性产品:

查看所有亚型
Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SMCC (GMP) is the GMP level of SMCC (HY-42360). GMP guidelines are used to produce SMCC (HY-42360) (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. SMCC (GMP) is a protein crosslinker. SMCC (GMP) contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.

体外研究
(In Vitro)

SMCC 或 sulfo-SMCC 可用于偶联海兔血蓝蛋白 (KLH) 和卵清蛋白 (OVA)。偶联体系中，将 300 μl KLH 或 OVA（3 mg）和 30 μl SMCC 或 sulfo-SMCC (终浓度为0.1 mM) 加入PBS中，终体积为 3 ml[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

SMCC 相关抗体:
体内研究
(In Vivo)

通过 SMCC 结合方法，在小鼠中注射抗原偶联的同基因脾单核细胞，能够诱导对整个蛋白质或肽抗原的强烈免疫反应[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

334.32

Formula

C16H18N2O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SMCC 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SMCC (GMP)64987-85-5ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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