2. Others GPCR/G Protein Neuronal Signaling
  3. Reference Standards MCHR1 (GPR24)
  4. SNAP 94847 hydrochloride (Standard)

SNAP 94847 hydrochloride (Standard) 是 SNAP 94847 (hydrochloride) (HY-107625A) 的分析标准品。本产品用于研究及分析应用。SNAP 94847 hydrochloride 是一种具有抗抑郁样活性的新型高亲和力选择性黑色素浓缩激素受体1 (MCHR1) 拮抗剂。SNAP 94847 hydrochloride 以高亲和力结合大小鼠 MCHR1，与其他 GPCR，离子通道，酶和转运蛋白具有最小的交叉反应性。SNAP 94847 hydrochloride 是 MCH 诱发的肌醇磷酸形成的高亲和力拮抗剂 (pA2=7.81)。

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SNAP 94847 hydrochloride (Standard)

SNAP 94847 hydrochloride (Standard) Chemical Structure

CAS No. : 1781934-47-1

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SNAP 94847 hydrochloride (Standard) 相关抗体

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生物活性

SNAP 94847 hydrochloride (Standard) is the analytical standard of SNAP 94847 (hydrochloride) (HY-107625A). This product is intended for research and analytical applications. SNAP 94847 hydrochloride is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. SNAP 94847 hydrochloride binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters[1][3].

IC50 & Target

Ki: 2.2 nM (MCHR1); Kd: 530 pM (MCHR1)[3]
分子量

515.03

Formula

C29H33ClF2N2O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SNAP 94847 hydrochloride (Standard) 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SNAP 94847 hydrochloride (Standard)1781934-47-1Reference StandardsMCHR1 (GPR24)Melanin concentrating hormone receptor 1AntidepressantanxiolyticanxietyInhibitorinhibitorinhibit

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