2. Metabolic Enzyme/Protease
  3. HMG-CoA Reductase (HMGCR)
  4. SQ-33600

SQ-33600 是一种 HMG-CoA 还原酶抑制剂。SQ-33600 具有降胆固醇的活性。SQ-33600 具有细胞类型选择性，对大鼠肝细胞的抑制活性 (IC50: 93 nM) 远高于人皮肤成纤维细胞 (IC50: 14200 nM)。SQ-33600 可用于高胆固醇血症等疾病的研究。

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SQ-33600

SQ-33600 Chemical Structure

CAS No. : 133983-25-2

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SQ-33600 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SQ-33600 is an HMG-CoA reductase inhibitor. SQ-33600 has cholesterol-lowering activity. SQ-33600 possesses cell-type selectivity, with much higher inhibitory activity on rat hepatocytes (IC50: 93 nM) than on human skin fibroblasts (IC50: 14200 nM). SQ-33600 can be used in the research of diseases such as hypercholesterolemia[1][2].

分子量

487.37

Formula

C23H21FNNa2O5P
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SQ-33600 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SQ-33600133983-25-2SQ33600SQ 33600HMG-CoA Reductase (HMGCR)hepatocytesskin fibroblastshypercholesterolemiaInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-19107
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