2. 疾病领域
  3. 神经系统疾病
  4. SR-1815

SR-1815 是一种小分子多激酶抑制剂。SR-1815 通过调控剪接等机制，在 Syngap1 单倍体不足的疾病模型中，有效恢复 SynGAP 蛋白至正常水平，进而纠正由该基因缺陷导致的突触和神经元网络水平的功能异常。SR-1815 可用于研究脑部疾病。

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SR-1815

SR-1815 Chemical Structure

CAS No. : 2636710-78-4

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SR-1815 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SR-1815 is a small molecule multi-kinase inhibitor. SR-1815, through mechanisms such as splicing regulation effectively restores the SynGAP protein to normal levels in the disease model with Syngap1 haploinsufficiency, thereby correcting the functional abnormalities at the synaptic and neuronal network levels caused by the deficiency of this gene. SR-1815 can be used for the study of brain diseases[1].

分子量

379.46

Formula

C21H25N5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SR-1815 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SR-18152636710-78-4SR1815SR 1815OthersEndo-GeneScreenSYNGAP1HaploinsufficiencyPhenotypic screeningSplicing modulationMultikinase inhibitorNeurodevelopmental disordersInhibitorinhibitorinhibit

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