2. Others Anti-infection Metabolic Enzyme/Protease Apoptosis
  3. Antibiotic Necroptosis Isotope-Labeled Compounds Bacterial Apoptosis Cytochrome P450
  4. Sulfaphenazole-d4

Sulfaphenazole-d4 是氘代标记的 Sulfaphenazole (HY-B1218)。Sulfaphenodium 是一种选择性的人 CYP2C9 酶抑制剂。Sulfaphenazole 是一种细胞保护剂，可防止光诱导的光感受器死亡。Sulfaphenazole 抑制光诱导的坏死和线粒体应激引发的细胞凋亡。Sulfaphenazole 是一种非专利磺酰胺抗生素，通过增强 M1 巨噬细胞活性发挥杀菌活性。Sulfaphenazole 可以显着减少梗塞面积并恢复缺血和再灌注后的缺血后冠状动脉血流。

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Sulfaphenazole-d<sub>4</sub>

Sulfaphenazole-d4 Chemical Structure

CAS No. : 2702538-04-1

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Other Forms of Sulfaphenazole-d4:

Sulfaphenazole-d4 相关抗体

Top Publications Citing Use of Products

查看 Antibiotic 亚型特异性产品:

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

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CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

  • 生物活性

  • 纯度 & 产品资料

生物活性

Sulfaphenazole-d4 is the deuterium labeled Sulfaphenazole (HY-B1218). Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion[1][2][3].

产品应用

1. 该化合物可作为示踪剂。
2. 该化合物可作为 NMR、GC-MS 或 LC-MS 分析中的内标品，用于定量分析。
体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Sulfaphenazole-d4 相关抗体:
分子量

318.39

Formula

C15H10D4N4O2S
CAS 号
非标记 CAS
中文名称

磺胺苯吡唑-d4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Sulfaphenazole-d4 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulfaphenazole-d42702538-04-1磺胺苯吡唑-d4AntibioticNecroptosisIsotope-Labeled CompoundsBacterialApoptosisCytochrome P450CYPsInhibitorinhibitorinhibit

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