2. 疾病领域
  3. 其他
  4. T3SS-IN-6

T3SS-IN-6 是噻唑烷-2-氰酰胺衍生物，也是靶向稻黄单胞菌水稻致病变种 (Xoo) 的 III 型分泌系统 (T3SS) 抑制剂。T3SS-IN-6 对 Xoo 的生长无影响。T3SS-IN-6 对家蚕和蚯蚓无可检测的急性毒性。

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T3SS-IN-6

T3SS-IN-6 Chemical Structure

CAS No. : 2231764-36-4

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T3SS-IN-6 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

T3SS-IN-6 is a thiazolidin-2-cyanamide derivative and type III secretion system (T3SS) inhibitor targeting Xanthomonas oryzae pv. oryzae (Xoo). T3SS-IN-6 exhibits no effect on Xoo growth. T3SS-IN-6 shows no measurable acute toxicity to silkworms and earthworms[1].

体外研究
(In Vitro)

T3SS-IN-6 (II-2) (100-200 μM; 2 h) 显著抑制 Xoo 的 III 型分泌系统（T3SS）介导的荧光素酶活性[1]。
T3SS-IN-6 (100-200 μM; 24 h) 显著抑制 Xoo 在本氏烟 (Nicotiana benthamiana)叶片中诱导的超敏反应[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

T3SS-IN-6 相关抗体:
体内研究
(In Vivo)

T3SS-IN-6 (II-2) (25-200 μg/mL；桑叶浸泡法；单次给药；96 h) 对家蚕 (Bombyx mori) 幼虫模型无急性毒性，24-96 h 的 LC50 值均大于 200 μg/mL[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Bombyx mori larvae[1]
Dosage: 25, 50, 100, 200 μg/mL
Administration: Orali via diet
Result: No mortality or visible toxic symptoms were observed in silkworm larvae at any tested concentration over 96 h.
The LC50 values at 24, 48, 72 and 96 h were all greater than 200 μg/mL.
分子量

342.33

Formula

C15H10N4O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

T3SS-IN-6 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

T3SS-IN-62231764-36-4Otherstype III secretion systemearthwormsXanthomonas oryzae pv. oryzaesilkwormsInhibitorinhibitorinhibit

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目录号：
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