1. Immunology/Inflammation
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  3. Triptohypol E

Triptohypol E 是一种三萜类化合物和一氧化氮生成抑制剂,可从兴安杜鹃 (Rhododendron dauricum L.) 的叶片中分离得到。Triptohypol E 以剂量依赖的方式抑制 LPS 刺激的巨噬细胞中一氧化氮的生成。

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Triptohypol E

Triptohypol E Chemical Structure

CAS No. : 268541-25-9

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  • 生物活性

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生物活性

Triptohypol E is a triterpenoid compound and nitric oxide production inhibitor that can be isolated from the leaves of Rhododendron dauricum L. Triptohypol E inhibits nitric oxide production in LPS-stimulated macrophages in a dose-dependent manner[1].

体外研究
(In Vitro)

Triptohypol E (30 μM; 24 h) 对 RAW 264.7 细胞无细胞毒性[1]
Triptohypol E (3-30 μM; 2 h 预孵育, 与 LPS 共孵育 24 h) 可剂量依赖性地抑制 LPS 刺激的 RAW 264.7 细胞中 NO 的生成[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: RAW 264.7
Concentration: 30 μM
Incubation Time: 24 h
Result: Showed no cytotoxicity toward RAW 264.7 cells.
分子量

456.74

Formula

C31H52O2

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Triptohypol E
目录号:
HY-N17528
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