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  2. Drug Derivative Myosin
  3. Tubercidin 5'-triphosphate

Tubercidin 5'-triphosphate  (Synonyms: 7-Deazaadenosine 5'-triphosphate)

目录号: HY-134248
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Tubercidin 5'-triphosphate (7-Deazaadenosine 5'-triphosphate) (Compound II) 是一种 ATP (HY-B2176) 类似物。Tubercidin 5'-triphosphate 可被 Myosin B 水解。Tubercidin 5'-triphosphate 诱导兔腰大肌肌原纤维发生微弱收缩。

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Tubercidin 5'-triphosphate

Tubercidin 5'-triphosphate Chemical Structure

CAS No. : 10058-66-9

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Other Forms of Tubercidin 5'-triphosphate:

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生物活性

Tubercidin 5'-triphosphate (7-Deazaadenosine 5'-triphosphate) (Compound II) is an ATP (HY-B2176) analogue. Tubercidin 5'-triphosphate is hydrolyzable by Myosin B. Tubercidin 5'-triphosphate induces weak contraction of rabbit psoas myofibrils[1].

体外研究
(In Vitro)

Tubercidin 5'-triphosphate (0.15 mM) 可在高离子强度、含 Ca2+ 的条件下 (0.6 M KCl, 7 mM CaCl2, pH 7.0, 20°C) 被兔骨骼肌肌球蛋白 B 水解,其水解速率为 ATP 水解速率的 49%[1]
Tubercidin 5'-triphosphate (0.15 mM) 可在低离子强度、含 Mg2+ 的条件下被兔骨骼肌肌球蛋白 B 水解,(0.075 M KCl, 2 mM MgCl2, pH 7.0, 20°C),其水解速率为 ATP 水解速率的 270%[1]
Tubercidin 5'-triphosphate (0.1 mM) 可在 0.04 M K+Cl、2 mM MgCl2、pH 7.0、23°C 条件下诱导兔腰大肌肌原纤维发生微弱收缩,这可通过细微收缩带的形成得到证明[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

506.19

Formula

C11H17N4O13P3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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