1. GPCR/G Protein
  2. LPL Receptor
  3. VPC 23153

VPC 23153 是一种 S1P4 受体激动剂和血管收缩剂。VPC 23153 可激活 S1P4 受体,从而触发血管收缩。VPC 23153 诱导肺动脉收缩。VPC 23153 可用于肺动脉高压的相关研究。

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VPC 23153

VPC 23153 Chemical Structure

CAS No. : 787582-98-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

VPC 23153 is a S1P4 receptor agonist and vasoconstrictor. VPC 23153 activates the S1P4 receptor, thereby triggering vasoconstriction. VPC 23153 induces pulmonary artery contraction. VPC 23153 can be used in studies related to pulmonary arterial hypertension[1].

IC50 & Target[1]

S1PR4

 

体外研究
(In Vitro)

VPC 23153 (0.01-3 μM) 可在离体灌流的正常血压大鼠肺中诱导剂量依赖性血管收缩[1]
VPC 23153 (0.1-10 μM) 可诱导慢性缺氧大鼠的离体肺动脉 (而非肾动脉或肠系膜动脉) 产生浓度依赖性收缩[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

369.40

Formula

C17H28N3O4P

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
VPC 23153
目录号:
HY-W040167
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