1. Anti-infection Apoptosis
  2. Fungal Apoptosis
  3. Xanthochymol

Xanthochymol 是一种抗真菌剂,被发现存在于玫瑰书带木 (Clusia rosea) 中。Xanthochymol 可以诱导真菌细胞凋亡 (apoptosis)。

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Xanthochymol

Xanthochymol Chemical Structure

CAS No. : 52617-32-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Xanthochymol is an antifungal agent found in Clusia rosea. Xanthochymol can induce fungal apoptosis[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
4 μg/mL
Compound: 7
Cytotoxicity against human A549 cells after 3 days by SRB assay
Cytotoxicity against human A549 cells after 3 days by SRB assay
[PMID: 20232858]
DU-145 IC50
4 μg/mL
Compound: 7
Cytotoxicity against human DU145 cells after 3 days by SRB assay
Cytotoxicity against human DU145 cells after 3 days by SRB assay
[PMID: 20232858]
KB IC50
4.6 μg/mL
Compound: 7
Cytotoxicity against human vincristine-resistant KB cells overexpressing p-glycoprotein after 3 days by SRB assay
Cytotoxicity against human vincristine-resistant KB cells overexpressing p-glycoprotein after 3 days by SRB assay
[PMID: 20232858]
KB IC50
5 μg/mL
Compound: 7
Cytotoxicity against human KB cells after 3 days by SRB assay
Cytotoxicity against human KB cells after 3 days by SRB assay
[PMID: 20232858]
LNCaP ED50
8 μM
Compound: 14
Growth inhibition of human LNCAP cells xenografted in ip dosed NCr nu/nu mouse administered once daily from day 3 to 6 after implantation measured on day 7 by MTT-based hollow-fiber test
Growth inhibition of human LNCAP cells xenografted in ip dosed NCr nu/nu mouse administered once daily from day 3 to 6 after implantation measured on day 7 by MTT-based hollow-fiber test
[PMID: 19161316]
SW480 IC50
8.3 μM
Compound: 4
Cytotoxicity against human SW480 cells after 72 hrs by MTT assay
Cytotoxicity against human SW480 cells after 72 hrs by MTT assay
[PMID: 15787435]
U-251 IC50
2.3 μM
Compound: 6
Cytotoxicity against human U251MG cells assessed as reduction in cell viability after 72 hrs by CyQuant dye-based assay
Cytotoxicity against human U251MG cells assessed as reduction in cell viability after 72 hrs by CyQuant dye-based assay
[PMID: 28729053]
分子量

602.80

Formula

C38H50O6

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Xanthochymol
目录号:
HY-178255
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