1. Metabolic Enzyme/Protease
  2. PAI-1
  3. XR 5118 hydrochloride

XR 5118 hydrochloride 是一种纤溶酶原激活剂抑制剂 1 (PAI-1) 的抑制剂 (IC50: 12 µM)。XR5118 hydrochloride 与 PAI-1 结合并降低血浆 PAI-1 活性水平。XR5118 hydrochloride 促进内源性溶栓作用并抑制血栓聚集。XR 5118 hydrochloride 可用于癌症和血栓性疾病的研究。

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XR 5118 hydrochloride

XR 5118 hydrochloride Chemical Structure

CAS No. : 174766-49-5

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  • 生物活性

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生物活性

XR 5118 hydrochloride is an inhibitor of plasminogen activator inhibitor 1 (PAI-1) (IC50: 12 µM). XR5118 binds to PAI-1 and reduces plasma PAI-1 activity levels. XR5118 hydrochloride promotes endogenous thrombolysis and inhibits thrombus accretion. XR 5118 hydrochloride can be used for research of cancer and thrombotic disease[1][2].

分子量

435.99

Formula

C20H22ClN3O2S2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
XR 5118 hydrochloride
目录号:
HY-117537
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