2. Metabolic Enzyme/Protease
  3. MetAP
  4. YOK24

YOK24 是一种具有口服活性的 MetAP2 抑制剂和抗阿米巴剂。YOK24 可与 MetAP2 共价结合并抑制其肽酶活性，而 MetAP2 是溶组织内阿米巴增殖所必需的蛋白质。YOK24 可用于阿米巴病的研究。

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YOK24

YOK24 Chemical Structure

CAS No. : 3075693-57-8

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

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YOK24 相关抗体

Top Publications Citing Use of Products

查看 MetAP 亚型特异性产品:

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MetAP2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

YOK24 is an orally active MetAP2 inhibitor and anti-amoebic agent. YOK24 binds covalently to MetAP2 and inhibits its peptidase activity, where MetAP2 is a protein essential for the proliferation of *Entamoeba histolytica*. YOK24 can be used in the research of amoebiasis[1].

体外研究
(In Vitro)

YOK24 可强效抑制溶组织内阿米巴的生长，其 ED50 为 15.5 nM，且在与仓鼠肝微粒体孵育后仍能保持该活性[1]。
YOK24 (10 μM) 对人肝癌 Huh-7 细胞无细胞毒性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

YOK24 相关抗体:
分子量

324.37

Formula

C17H24O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

YOK24 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

YOK243075693-57-8YOK 24YOK-24MetAPMethionine AminopeptidaseMetAP2human hepatocellular carcinoma cellshepatic metabolismHuh-7hamstersEntamoeba histolyticacytochrome P450amebic liver abscessamebiasismicrosomesInhibitorinhibitorinhibit

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目录号：
HY-181643
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