SELICICLIB
- CAS No.
- 186692-44-4
- Chemical Name:
- SELICICLIB
- Synonyms
- (+/-)-ROSCOVITINE;(Rac)-Roscovitine;2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol;2-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-Butanol;1-Butanol, 2-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-
- CBNumber:
- CB22463665
- Molecular Formula:
- C19H26N6O
- Molecular Weight:
- 354.45
- MDL Number:
- MFCD02266401
- MOL File:
- 186692-44-4.mol
| Product description | Number | Pack Size | Price |
| SELICICLIB 95.00% | KIN0002581 | 10MG | $817.39 |
| Boiling point | 577.5±60.0 °C(Predicted) |
|---|---|
| Density | 1.25 |
| pka | 14.56±0.10(Predicted) |
| FDA UNII | AIR55KO85E |
SELICICLIB Chemical Properties,Uses,Production
Uses
(Rac)-Roscovitine ((Rac)-Seliciclib) is a selective cyclin-dependent kinases (CDKs) inhibitor. (Rac)-Roscovitine binds to the active sites of CDKs competitively with ATP, inhibiting the phosphorylation activity of CDKs. (Rac)-Roscovitine induces apoptosis in cancer cells. (Rac)-Roscovitine is promising for research of cancers or other diseases associated with CDK dysregulation, such as neurodegenerative diseases, cardiac disorders, viral and protozoan infections, glomerulonephritis, and chronic inflammation[1].
References
[1] Jorda R, et al. Pyrazolo[4,3-d]pyrimidine bioisostere of roscovitine: evaluation of a novel selective inhibitor of cyclin-dependent kinases with antiproliferative activity. J Med Chem. 2011 Apr 28;54(8):2980-93.
SELICICLIB Preparation Products And Raw materials
Raw materials
Preparation Products
SELICICLIB Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 8510 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43339 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2922 | 55 | |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7778 | 56 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 8022 | 55 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
