PD0332991이세티오네이트
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PD0332991이세티오네이트 속성
- 저장 조건
- room temp
- 용해도
- ≥28.7 mg/mL in DMSO; insoluble in EtOH; ≥26.8 mg/mL in H2O
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
- 수용성
- H2O: 5mg/mL, clear
- InChIKey
- LYYVFHRFIJKPOV-UHFFFAOYSA-N
- SMILES
- C(CO)S(O)(=O)=O.O=C1C(=C(C)C2=CN=C(NC3N=CC(N4CCNCC4)=CC=3)N=C2N1C1CCCC1)C(=O)C
- CAS 데이터베이스
- 827022-33-3
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 유엔번호(UN No.) | UN 2811 6.1 / PGIII | ||
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| WGK 독일 | 3 |
| 그림문자(GHS): |
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| 신호 어: | Danger | ||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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PD0332991이세티오네이트 C화학적 특성, 용도, 생산
용도
PD 0332991 isethionate has been used:- to incubate MCF10A cells to verify cyclin D1 inhibition of autophagy involved cyclin-dependent kinase activity
- as a cyclin dependent kinase 4 (CDK4) inhibitor to study its anticonvulsive property in Drosophila
- to mimic the inhibitory effect of 5α-dihydrotestosterone (DHT) on HPr-1AR cell cycle progression and growth
Biochem/physiol Actions
PD 0332991 is a potent selective inhibitor of cyclin dependent kinases CDK4 and CDK6 with in vitro IC50 = 11 nM (CDK4) and 16 nM (CDK6). PD 0332991 induces G1 arrest in retinoblastoma (Rb)-positive tumor cells.PD0332991이세티오네이트 준비 용품 및 원자재
원자재
준비 용품
PD0332991이세티오네이트 공급 업체
글로벌( 208)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 |
sales@capot.com | China | 29735 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29847 | 58 |
| TianYuan Pharmaceutical CO.,LTD | +86-755-23284190 13684996853 |
sales@tianpharm.com | CHINA | 304 | 58 |
| Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 965 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19552 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 20284 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 |
info@finetechnology-ind.com | China | 9629 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 |
shawn@hirisunpharm.com | CHINA | 9911 | 58 |
PD0332991이세티오네이트 관련 검색:
보노프라잔푸마라테 보노프라자 파록세틴메실레이트 칼륨 피로인산염
Olaparib
Abemaciclib mesylate (LY2835219)
ABT 263
Trametinib
Ribociclib
MK-2206 2HCl
Rivaroxaban
Vonoprazan fumarate
Paroxetine
4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
tert-Butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
Roscovitine
PD 0332991 HCl
BML-259