100009-77-6 (5-methoxy-2-(5,6,7-trimethoxyisoquinolin-1-yl)benzoic acid,Benzoic acid, 5-methoxy-2-(5,6,7-trimethoxy-1-isoquinolinyl)-)

快速询单

结构式：

5-methoxy-2-(5,6,7-trimethoxyisoquinolin-1-yl)benzoic acidMOL文件

CAS号：

100009-77-6

中文名称：

5-methoxy-2-(5,6,7-trimethoxyisoquinolin-1-yl)benzoic acid

英文名称：

Benzoic acid, 5-methoxy-2-(5,6,7-trimethoxy-1-isoquinolinyl)-

分子式：

C₂₀H₁₉NO₆

分子量：

369.367965936661

5-methoxy-2-(5,6,7-trimethoxyisoquinolin-1-yl)benzoic acid(100009-77-6)名称与标识符

名称

中文别名：

5-methoxy-2-(5,6,7-trimethoxyisoquinolin-1-yl)benzoic acid;

英文别名：

Benzoic acid, 5-methoxy-2-(5,6,7-trimethoxy-1-isoquinolinyl)-;

标识符

InChIKey：

YMURCLQMGSSPGF-UHFFFAOYSA-N

Inchi：

1S/C20H19NO6/c1-24-11-5-6-12(15(9-11)20(22)23)17-14-10-16(25-2)19(27-4)18(26-3)13(14)7-8-21-17/h5-10H,1-4H3,(H,22,23)

SMILES：

C(O)(=O)C1=CC(OC)=CC=C1C1C2=C(C(OC)=C(OC)C(OC)=C2)C=CN=1

5-methoxy-2-(5,6,7-trimethoxyisoquinolin-1-yl)benzoic acid(100009-77-6)合成路线

合成路线：1 步

反应条件：

1.1 Reagents: Silver oxide (Ag2O) Solvents: Chloroform

参考文献：

The structure of 2,3-dihydromenisporphine and the synthesis of dauriporphine, oxoisoaporphine alkaloids from Menispermum dauricum DC

Kunitomo, Jun Ichi; et al, Chemical & Pharmaceutical Bulletin, 1985, 33(7), 2778-82

合成路线：2 步

100009-76-5

100009-77-6

88142-60-3

反应条件：

1.1 Reagents: Hydrochloric acid Solvents: Water
2.1 Reagents: Silver oxide (Ag2O) Solvents: Chloroform

参考文献：

The structure of 2,3-dihydromenisporphine and the synthesis of dauriporphine, oxoisoaporphine alkaloids from Menispermum dauricum DC

Kunitomo, Jun Ichi; et al, Chemical & Pharmaceutical Bulletin, 1985, 33(7), 2778-82

合成路线：3 步

反应条件：

1.1 Solvents: Methanol
2.1 Reagents: Hydrochloric acid Solvents: Water
3.1 Reagents: Silver oxide (Ag2O) Solvents: Chloroform

参考文献：

The structure of 2,3-dihydromenisporphine and the synthesis of dauriporphine, oxoisoaporphine alkaloids from Menispermum dauricum DC

Kunitomo, Jun Ichi; et al, Chemical & Pharmaceutical Bulletin, 1985, 33(7), 2778-82

合成路线：4 步

100009-78-7

100009-77-6

88142-60-3

反应条件：

1.1 Reagents: Potassium hydroxide Solvents: Ethanol
2.1 Solvents: Methanol
3.1 Reagents: Hydrochloric acid Solvents: Water
4.1 Reagents: Silver oxide (Ag2O) Solvents: Chloroform

参考文献：

The structure of 2,3-dihydromenisporphine and the synthesis of dauriporphine, oxoisoaporphine alkaloids from Menispermum dauricum DC

Kunitomo, Jun Ichi; et al, Chemical & Pharmaceutical Bulletin, 1985, 33(7), 2778-82

合成路线：5 步

100009-80-1

100009-77-6

88142-60-3

反应条件：

1.1 Reagents: Cuprous cyanide Solvents: Dimethylformamide
2.1 Reagents: Potassium hydroxide Solvents: Ethanol
3.1 Solvents: Methanol
4.1 Reagents: Hydrochloric acid Solvents: Water
5.1 Reagents: Silver oxide (Ag2O) Solvents: Chloroform

参考文献：

The structure of 2,3-dihydromenisporphine and the synthesis of dauriporphine, oxoisoaporphine alkaloids from Menispermum dauricum DC

Kunitomo, Jun Ichi; et al, Chemical & Pharmaceutical Bulletin, 1985, 33(7), 2778-82

合成路线：6 步

100009-74-3

100009-77-6

88142-60-3

反应条件：

1.1 Reagents: Phosphorus oxychloride Solvents: Toluene
2.1 Reagents: Cuprous cyanide Solvents: Dimethylformamide
3.1 Reagents: Potassium hydroxide Solvents: Ethanol
4.1 Solvents: Methanol
5.1 Reagents: Hydrochloric acid Solvents: Water
6.1 Reagents: Silver oxide (Ag2O) Solvents: Chloroform

参考文献：

The structure of 2,3-dihydromenisporphine and the synthesis of dauriporphine, oxoisoaporphine alkaloids from Menispermum dauricum DC

Kunitomo, Jun Ichi; et al, Chemical & Pharmaceutical Bulletin, 1985, 33(7), 2778-82

合成路线：7 步

反应条件：

1.1 Reagents: Sodium hydroxide Solvents: Diethyl ether , Water
2.1 Reagents: Phosphorus oxychloride Solvents: Toluene
3.1 Reagents: Cuprous cyanide Solvents: Dimethylformamide
4.1 Reagents: Potassium hydroxide Solvents: Ethanol
5.1 Solvents: Methanol
6.1 Reagents: Hydrochloric acid Solvents: Water
7.1 Reagents: Silver oxide (Ag2O) Solvents: Chloroform

参考文献：

The structure of 2,3-dihydromenisporphine and the synthesis of dauriporphine, oxoisoaporphine alkaloids from Menispermum dauricum DC

Kunitomo, Jun Ichi; et al, Chemical & Pharmaceutical Bulletin, 1985, 33(7), 2778-82

合成路线：8 步

74317-85-4

100009-77-6

88142-60-3

反应条件：

1.1 Reagents: Thionyl chloride
2.1 Reagents: Sodium hydroxide Solvents: Diethyl ether , Water
3.1 Reagents: Phosphorus oxychloride Solvents: Toluene
4.1 Reagents: Cuprous cyanide Solvents: Dimethylformamide
5.1 Reagents: Potassium hydroxide Solvents: Ethanol
6.1 Solvents: Methanol
7.1 Reagents: Hydrochloric acid Solvents: Water
8.1 Reagents: Silver oxide (Ag2O) Solvents: Chloroform

参考文献：

The structure of 2,3-dihydromenisporphine and the synthesis of dauriporphine, oxoisoaporphine alkaloids from Menispermum dauricum DC

Kunitomo, Jun Ichi; et al, Chemical & Pharmaceutical Bulletin, 1985, 33(7), 2778-82