10421-76-8 (纳斯科平,Nascopine)

快速询单

结构式：

纳斯科平MOL文件

CAS号：

10421-76-8

中文名称：

纳斯科平

英文名称：

Nascopine

分子式：

C₂₂H₂₃NO₇

分子量：

413.420526742935

纳斯科平(10421-76-8)名称与标识符

名称

英文别名：

1-alpha-2-methyl-8-methoxy-6,7-methylenedioxy-1-(6,7-dimethoxy-3-phthalidyl)-1,2,3,4-tetrahydroisoquinoline;α-Narcotine;Gnoscopine;dl-Narcotine;alpha-Gnoscopine;Noscapine dl-form;6,7-Dimethoxy-3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2-benzofuran-1(3H)-one;Longactin;6,7-dimethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-isobenzofuran-1-one;6,7-dimethoxy-3-(4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuran-1(3H)-one;Narcotine alkaloid;(-)-noscapine;Narcotine, (+-)-;( -)-Nosca;

标识符

InChIKey：

AKNNEGZIBPJZJG-UHFFFAOYSA-N

Inchi：

1S/C22H23NO7/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18/h5-6,9,17-18H,7-8,10H2,1-4H3

SMILES：

O1C(C2C(=C(C=CC=2C1C1C2C(=C3C(=CC=2CCN1C)OCO3)OC)OC)OC)=O

纳斯科平(10421-76-8)物化性质

计算特性

氢键供体数量 : 0
氢键受体数量 : 8
可旋转化学键数量 : 4
重原子数量 : 30
复杂度 : 647
拓扑分子极性表面积 : 75.7

纳斯科平(10421-76-8)国际标准相关数据

EINECS：

96350

纳斯科平(10421-76-8)相关文献

1. 285. Stereoisomerides of narcotine and hydrastine
M. A. Marshall,F. L. Pyman,Robert Robinson J. Chem. Soc. 1934 1315
2. 192. The absolute stereochemistry of narcotine and narcotoline
A. R. Battersby,H. Spencer J. Chem. Soc. 1965 1087
3. LXXXIII.—Synthesis and resolution of gnoscopine (dl-narcotine)
William Henry Perkin,Robert Robinson J. Chem. Soc. Trans. 1911 99 775
4. CXCIV.—Synthetical experiments in the group of the isoquinoline alkaloids. Part IV. The synthesis of β-gnoscopine
Edward Hope,Robert Robinson J. Chem. Soc. Trans. 1914 105 2085
5. Studies on the syntheses of heterocyclic compounds. Part 678. Photoracemisation and photoepimerisation of the phthalidylisoquinoline alkaloids (–)-α-narcotine and (–)-β-hydrastine
Tetsuji Kametani,Hitoshi Inoue,Toshio Honda,Tsutomu Sugahara,Keiichiro Fukumoto J. Chem. Soc. Perkin Trans. 1 1977 374
6. Alkaloid biosynthesis. Part XII. The biosynthesis of narcotine
A. R. Battersby,M. Hirst,D. J. McCaldin,R. Southgate,J. Staunton J. Chem. Soc. C 1968 2163
7. Spectrofluorimetric analysis of mixtures of the principal ***** alkaloids
R. A. Chalmers,G. A. Wadds Analyst 1970 95 234
8. CXIII. On the composition of narcotine, and some of its products of decomposition by the action of bichloride of platinum
J. Blyth Mem. Proc. Chem. Soc. 1843 2 163
9. XLV.—The influence of papaverine on the optical activity of narcotine in acid solution
Harold Edward Annett J. Chem. Soc. Trans. 1923 123 376
10. Organic chemistry
J. Chem. Soc. Abstr. 1911 100 i1