117106-39-5 (司氟沙星,(1R,2S)-1-(Naphthalen-1-yl)-2-(naphthalen-2-yl)ethane-1,2-diamine)

快速询单

结构式：

司氟沙星MOL文件

CAS号：

117106-39-5

中文名称：

司氟沙星

英文名称：

(1R,2S)-1-(Naphthalen-1-yl)-2-(naphthalen-2-yl)ethane-1,2-diamine

分子式：

C₂₂H₂₀N₂

分子量：

312.407605171204

简介：

司氟沙星（sparfloxacin）抗菌谱广，对革兰阴性菌抗菌活性与环丙沙星相似，对阳性菌强与环丙沙星和氧氟沙星，对厌氧菌，支原体，衣原体作用强，并对多种耐药菌也有效。口服吸收后在组织内浓度高，半衰期长，用于敏感菌，厌氧菌，支原体及衣原体的感染。近年有报道可发生严重光敏反应，应慎用。

司氟沙星(117106-39-5)名称与标识符

名称

中文别名：

meso-1,2-二(萘基)乙二胺;Meso-1,2-双(1-萘)乙烯二胺;内消旋-1,2 - 二（萘基）乙二胺;司氟沙星;MESO-1,2-BIS(NAPHTHYL)ETHYLENEDIAMINE,MIN.98%;

英文别名：

1,2-Ethanediamine,1,2-di-1-naphthalenyl-, (1R,2S)-rel-;meso-1,2-Bis(1-naphthyl)ethylenediamine;NULL;1,2-DI-1-NAPHTHYLETHANE-1,2-DIAMINE;AURORA KA-7324;SALOR-INT L300918-1EA;meso-1,2-Bis(1-naphthyl)ethylenediamine,99%;meso-1,2-Bis(naphthyl)ethylenediamine, min. 98%;Meso-1,2-Bis(1-naphthyl)ethylenediaMine,Min.98%;meso-1,2-Bis(1-naphthyl)ethylenediamine, min. 98%;117106-39-5;1,2-Ethanediamine, 1,2-di-1-naphthalenyl-, (1R,2S)-rel-;(1R,2S)-1,2-dinaphthalen-1-ylethane-1,2-diamine;rel-(1R,2S)-1,2-Di(naphthalen-1-yl)ethane-1,2-diamine;(1R,2S)-1,2-Di(naphthalen-1-yl)ethane-1,2-diamine;CS-0106219;(1R,2S)-1,2-bis(naphthalen-1-yl)ethane-1,2-diamine;

标识符

MDL：

MFCD05150370

InChIKey：

VVJVMUUCGDSHBT-SZPZYZBQSA-N

Inchi：

1S/C22H20N2/c23-21(19-13-5-9-15-7-1-3-11-17(15)19)22(24)20-14-6-10-16-8-2-4-12-18(16)20/h1-14,21-22H,23-24H2/t21-,22+

SMILES：

N[C@H](C1=CC=CC2C=CC=CC1=2)[C@H](C1=CC=CC2C=CC=CC1=2)N

司氟沙星(117106-39-5)物化性质

实验特性

LogP : 6.09340
PSA : 52.04000
沸点 : 529.8°Cat760mmHg
熔点 : 174-177 °C
闪点 : 330.1°C
颜色与性状 : 无可用
溶解性 : 无可用
敏感性 : air sensitive
密度 : g/cm3

计算特性

精确分子量 : 312.16300
氢键供体数量 : 0
氢键受体数量 : 3
可旋转化学键数量 : 1
同位素质量 : 312.163
重原子数量 : 25
复杂度 : 665
同位素原子数量 : 0
确定原子立构中心数量 : 0
不确定原子立构中心数量 : 0
确定化学键立构中心数量 : 0
不确定化学键立构中心数量 : 0
共价键单元数量 : 1
疏水参数计算参考值（XlogP） : 3.5
互变异构体数量 : 无
表面电荷 : 0
拓扑分子极性表面积 : 52A^2

司氟沙星(117106-39-5)安全信息

安全术语： S45-36/37/39-26
安全说明： S45
风险术语： R34
危险品标志： C
危害声明：H303吞入可能有害+H313皮肤接触可能有害+H333吸入可能对身体有害
警示性声明：P264+P280+P305+P351+P338+P337+P313
储存条件： storage at -4℃ (6-12weeks), longer storage period at -20℃ (1-2years)，0℃条件下运输
危险类别码： 34
信号词： warning

司氟沙星(117106-39-5)国际标准相关数据

EINECS：

司氟沙星(117106-39-5)推荐厂家更多厂家(5)

公司名称	手机号/电话	联系人	QQ	询单
上海瀚思化工有限公司	18939883912 021-34536277	顾经理	3003949364	询单
金锦乐（湖南）化学有限公司		金锦乐	1226360695	询单
上海依赫生物科技有限公司	17721395025 021-68882955	张经理	2423903095	询单
上海柯维化学技术有限公司	18901607656 021-64609169	白荷	3428632096	询单
上海阿拉丁生化科技股份有限公司	13167063860 13167063860	阿拉丁	3004013043	询单

司氟沙星(117106-39-5)相关文献

1. Catalytic enantioselective one-pot approach to cis- and trans-2,3-diaryl substituted 1,5-benzothiazepines
Sara Meninno,Ilaria Quaratesi,Chiara Volpe,Andrea Mazzanti,Alessandra Lattanzi Org. Biomol. Chem. 2018 16 6923

司氟沙星(117106-39-5)参考资料

Reaxys RN：

PubChem CID：

2734857

司氟沙星(117106-39-5) MSDS

基础信息

Name:	Meso-1 2-bis(1-naphthyl)ethylenediamine 99% Material Safety Data Sheet
Synonym:
CAS:	117106-39-5

Section 1 - Chemical Product ? MSDS Name:Meso-1 2-bis(1-naphthyl)ethylenediamine 99% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
117106-39-5	meso-1,2-Bis(1-naphthyl)ethylenediamin	99%	unlisted

Hazard Symbols: C
Risk Phrases: 34

Section 3 - HAZARDS IDENTIFICATION
? EMERGENCY OVERVIEW
Causes burns.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
? Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
? General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide.

Section 6 - ACCIDENTAL RELEASE MEASURES
? General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
? Handling:
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Corrosives area. Store under nitrogen.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
? Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 117106-39-5: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
?
Physical State: Solid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 177 - 178 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C22H20N2
Molecular Weight: 312.41

Section 10 - STABILITY AND REACTIVITY
? Chemical Stability:
Stable under normal temperatures and pressures. Light sensitive.
Conditions to Avoid:
Incompatible materials, light.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
? RTECS#:
CAS# 117106-39-5 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
meso-1,2-Bis(1-naphthyl)ethylenediamine - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION
?

Section 13 - DISPOSAL CONSIDERATIONS
? Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
?
IATA
Shipping Name: CORROSIVE SOLID, BASIC, ORGANIC, N.O.S.*
Hazard Class: 8
UN Number: 3263
Packing Group: III
IMO
Shipping Name: CORROSIVE SOLID, BASIC, ORGANIC, N.O.S.
Hazard Class: 8
UN Number: 3263
Packing Group: III
RID/ADR
Shipping Name: CORROSIVE SOLID, BASIC, ORGANIC, N.O.S.
Hazard Class: 8
UN Number: 3263
Packing group: III

Section 15 - REGULATORY INFORMATION
?
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 117106-39-5: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 117106-39-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 117106-39-5 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A