1-[4-[[3-氨基-5-[(4S)-4-氨基-2-氧杂-8-氮杂螺环[4.5]癸-8-基]-2-吡嗪基]硫代]-3,3-二氟-2,3-二氢-1H-吲哚-1-基]-乙酮(2169223-48-5)名称与标识符
名称
英文别名：
SHP2-IN-6;JAB3068;NSC827676;SHP2 Inhibitor JAB-3068;ETHANONE, 1-(4-((3-AMINO-5-((4S)-4-AMINO-2-OXA-8-AZASPIRO(4.5)DEC-8-YL)-2-PYRAZINYL)THIO)-3,3-DIFLUORO-2,3-DIHYDRO-1H-INDOL-1-YL)-;AKOS040757372;(S)-1-(4-(3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-ylthio)-3,3-difluoroindolin-1-yl)ethanone;GLXC-26924;JAB 3068 [WHO-DD];1-[4-[3-Amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl]pyrazin-2-yl]sulfanyl-3,3-difluoro-2H-indol-1-yl]ethanone;HY-131132;CHEMBL5095185;JAB-3068;Jab 3068;DA-77828;NSC-827676;HGYTYZKWKUXRKA-MRXNPFEDSA-N;2169223-48-5;V6Q7413SA8;CS-0129188;SCHEMBL19704279;JAB-3068 [WHO-DD];
标识符
InChIKey：
HGYTYZKWKUXRKA-MRXNPFEDSA-N
Inchi：
1S/C22H26F2N6O2S/c1-13(31)30-11-22(23,24)18-14(30)3-2-4-15(18)33-20-19(26)28-17(9-27-20)29-7-5-21(6-8-29)12-32-10-16(21)25/h2-4,9,16H,5-8,10-12,25H2,1H3,(H2,26,28)/t16-/m1/s1
SMILES：
S(C1=C([H])C([H])=C([H])C2=C1C(C([H])([H])N2C(C([H])([H])[H])=O)(F)F)C1C(N([H])[H])=NC(=C([H])N=1)N1C([H])([H])C([H])([H])C2(C([H])([H])OC([H])([H])[C@@]2([H])N([H])[H])C([H])([H])C1([H])[H]
2881489226 
![1-[4-[[3-氨基-5-[(4S)-4-氨基-2-氧杂-8-氮杂螺环[4.5]癸-8-基]-2-吡嗪基]硫代]-3,3-二氟-2,3-二氢-1H-吲哚-1-基]-乙酮结构式图片|2169223-48-5结构式图片](http://hg.y866.cn/compound/lib/scimg/cas/150/2169223-48-5.png?t=639020045751810745)
