2245848-05-7 ((Murizatoclax)

BO0V7196L2;Murizatoclax;Murizatoclax [USAN];AMG 397;BDBM470606;US10821115, Example 10;WHO 11281;Myeloid Cell Leukemia 1 Inhibitor AMG 397;MS-31374;Spiro(5,7-etheno-1H,11H-cyclobut(i)(1,4)oxazepino(3,4-f)(1,2,7)thiadiazacyclohexadecine-2(3H),1'(2'H)-naphthalen)-8(9H)-one, 6'-chloro-3',4',12,13,16,16a,17,18,18a,19-decahydro-16-methoxy-11,12-dimethyl-16-(((9aR)-octahydro-2H-pyrido(1,2-a)pyrazin-2-yl)methyl)-, 10,10-dioxide, (1'S,11R,12S,14E,16R,16aR,18aR)-;CS-0116455;MURIZATOCLAX [WHO-DD];AMG397;AKOS040745010;E6-thia-1,14-diazatetracyclo[14.7.2.03,6.019,24]pentacosa-8,16(25),17,19(24)-tetraene]-15'-one;(13S,31R,32R,4R,5E,8S,9R)-6'-CHLORO-4-METHOXY-8,9-DIMETHYL-4-(((9AR)-OCTAHYDRO-2H-PYRIDO(1,2-A)PYRAZIN-2-YL)METHYL)-3',4'-DIHYDRO-12H,14H,2'HSPIRO(10.LAMBDA.6-THIA-11-AZA-1(5,7)-(1,5)BENZOXAZEPINA-3(1,2)-CYCLOBUTANACYCLODODECAPHAN-5-ENE-13,1'-NAPHTHALENE)-10,10,12-TRIONE;HY-109184;(3'R,4S,6'R,7'R,8'E,11'S,12'R)-7'-[[(9aR)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-2-yl]methyl]-7-chloro-7'-methoxy-11',12'-dimethyl-13',13'-dioxospiro[2,3-dihydro-1H-naphthalene-4,22'-20-oxa-13;MCL-1 inhibitor AMG 397;NSC-845308;>>6-thia-1,14-diazatetracyclo[14.7.2.03,6.019,24]pentacosa-8,16(25),17,19(24)-tetraene]-15'-one;(13S,31R,32R,4R,5E,8S,9R)-6'-CHLORO-4-METHOXY-8,9-DIMETHYL-4-(((9AR)- OCTAHYDRO-2H-PYRIDO(1,2-A)PYRAZIN-2-YL)METHYL)-3',4'-DIHYDRO-12H,14H,2'HSPIRO( 10.LAMBDA.6-THIA-11-AZA-1(5,7)-(1,5)BENZOXAZEPINA-3(1,2)- CYCLOBUTANACYCLODODECAPHAN-5-ENE-13,1'-NAPHTHALENE)-10,10,12-TRIONE;SCHEMBL21040009;UNII-BO0V7196L2;G18013;NSC845308;AMG-397;(13S,31R,32R,4R,5E,8S,9R)-6'-Chloro-4-methoxy-8,9-dimethyl-4-(((9aR)-octahydro-2H-pyrido(1,2-a)pyrazin-2-yl)methyl)-3',4'-dihydro-12H,14H,2'Hspiro(10lambda6-thia-11-aza-1(5,7)-(1,5)benzoxazepina-3(1,2)-cyclobutanacyclododecaphan-5-ene-13,1'-naphthalene)-10,10,12-trione;MURIZATOCLAX [INN];EX-A9783;CHEMBL4650225;2245848-05-7;

BJTFTQIBRVBSBH-VCQPVEJUSA-N

1S/C42H57ClN4O5S/c1-29-8-6-18-42(51-3,27-45-20-21-46-19-5-4-10-35(46)25-45)37-14-11-33(37)24-47-26-41(17-7-9-31-22-34(43)13-15-36(31)41)28-52-39-16-12-32(23-38(39)47)40(48)44-53(49,50)30(29)2/h6,12-13,15-16,18,22-23,29-30,33,35,37H,4-5,7-11,14,17,19-21,24-28H2,1-3H3,(H,44,48)/b18-6+/t29-,30+,33-,35+,37+,41-,42-/m0/s1

ClC1C=CC2=C(C=1)CCC[C@@]12COC2C=CC3C(NS([C@H](C)[C@@H](C)CC=C[C@](CN4CCN5CCCC[C@@H]5C4)([C@@H]4CC[C@H]4CN(C=2C=3)C1)OC)(=O)=O)=O |t:27|