27037-34-9 (4-羟基-7-甲氧基喹啉-2-酮,4-Hydroxy-7-methoxy-1H-quinolin-2-one)

快速询单

结构式：

4-羟基-7-甲氧基喹啉-2-酮MOL文件

CAS号：

27037-34-9

中文名称：

4-羟基-7-甲氧基喹啉-2-酮

英文名称：

4-Hydroxy-7-methoxy-1H-quinolin-2-one

分子式：

C₁₀H₉NO₃

分子量：

191.183362722397

4-羟基-7-甲氧基喹啉-2-酮(27037-34-9)名称与标识符

名称

中文别名：

4-羟基-7-甲氧基喹啉-2-酮;2,4-二羟基-7-甲氧基喹啉;

英文别名：

4-Hydroxy-7-methoxy-1H-quinolin-2-one;4-Hydroxy-7-methoxy-2H-quinolin-2-one;4-Hydroxy-7-methoxyquinolin-2(1H)-one;2(1H)-Quinolinone,4-hydroxy-7-methoxy;2-hydroxy-7-methoxy-1H-quinolin-4-one;4-Hydroxy-7-methoxy-2(1H)-chinolin;4-hydroxy-7-methoxy-2-oxo-1,2-dihydroquinoline;4-Hydroxy-7-methoxycarbostyril;4-hydroxy-7-methoxyquinoline-2(1H)-one;7-methoxy-4-hydroxyquinoline-2(1H)-one;QUI088;2(1H)-Quinolinone, 4-hydroxy-7-methoxy-;7-Methoxyquinoline-2,4-diol;2-Hydroxy-7-methoxyquinolin-4(1H)-one;2,4-Dihydroxy-7-methoxyquinoline;4-hydroxy-7-methoxy-1,2-dihydroquinolin-2-one;FCH839437;RW1166;VQ10486;HQ11329;2(1H)-Quinolinone,4-hydrox;DS-10538;SCHEMBL743131;27037-34-9;AM20051015;AKOS002390458;FT-0638662;DTXSID30716066;MFCD00101261;J-515510;CS-0097851;SB36309;DB-006837;

标识符

MDL：

MFCD00101261

InChIKey：

RUWKOLGTLOFEMK-UHFFFAOYSA-N

Inchi：

1S/C10H9NO3/c1-14-6-2-3-7-8(4-6)11-10(13)5-9(7)12/h2-5H,1H3,(H2,11,12,13)

SMILES：

O(C)C1C=CC2C(=CC(NC=2C=1)=O)O

4-羟基-7-甲氧基喹啉-2-酮(27037-34-9)物化性质

实验特性

LogP : 1.24230
PSA : 62.32000
折射率 : 1.623
沸点 : 356.7℃/760mmHg
闪点 : 169.5°C
密度 : 1.355

计算特性

精确分子量 : 191.05800
氢键供体数量 : 2
氢键受体数量 : 3
可旋转化学键数量 : 1
同位素质量 : 191.058
重原子数量 : 14
复杂度 : 275
同位素原子数量 : 0
确定原子立构中心数量 : 0
不确定原子立构中心数量 : 0
确定化学键立构中心数量 : 0
不确定化学键立构中心数量 : 0
共价键单元数量 : 1
疏水参数计算参考值（XlogP） : 0.7
拓扑分子极性表面积 : 58.6

4-羟基-7-甲氧基喹啉-2-酮(27037-34-9)安全信息

危险品标志： Xn
危险类别码： 22

4-羟基-7-甲氧基喹啉-2-酮(27037-34-9)海关数据

海关编码：

2933499090

海关数据：

中国海关编码：

2933499090

概述：

2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

申报要素：

品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

Summary：

2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-羟基-7-甲氧基喹啉-2-酮(27037-34-9)推荐厂家更多厂家(22)

公司名称	手机号/电话	联系人	QQ	询单
上海绩祥生物科技有限公司	13093077543	陆经理	3985448220	询单
北京百灵威科技有限公司	18210857532	翟先生	3650742139	询单
上海瀚思化工有限公司	18939883912 021-34536277	顾经理	3003949364	询单
上海腾准生物科技有限公司	19821570922 021-34053661	张经理	3003871136	询单
南通众合化工新材料有限公司	18762756250 0513-55074056	胡经理	2369399482	询单
赫澎（上海）生物科技有限公司	13122891558 186-16545970	张硕	3418426269	询单
赫澎（上海）生物科技有限公司	13122891558 186-16545970	张硕	3418426269	询单
杰达维（上海）医药科技发展有限公司	13651849907 021-64340559	石小姐	3004189204	询单
金锦乐（湖南）化学有限公司		金锦乐	1226360695	询单
上海甄准生物科技有限公司	13816009161 021-68920155	姜经理13816009161	3001086693	询单

4-羟基-7-甲氧基喹啉-2-酮(27037-34-9) MSDS

基础信息

SECTION 1: Identification of the substance/mixture and of the company/undertaking
  Product identifiers
    Product name        : 4-Hydroxy-7-Methoxy-1H-Quinolin-2-One
    : CVT00065
    REACH No.        : A registration number is not available for this substance as the substance
    or its uses are exempted from registration, the annual tonnage does not
    require a registration or the registration is envisaged for a later
    registration deadline.

SECTION 2: Hazards identification
  Classification of the substance or mixture
  Classification according to Regulation (EC) No 1272/2008
    Acute toxicity, Oral (Category 4), H302
    For the full text of the H-Statements mentioned in this Section, see Section 16.
  Classification according to EU Directives 67/548/EEC or 1999/45/EC
    Xn Harmful        R22
    For the full text of the R-phrases mentioned in this Section, see Section 16.
  Label elements
  Labelling according Regulation (EC) No 1272/2008
    Pictogram
    Signal word        Warning
    Hazard statement(s)
    Harmful if swallowed.
    Precautionary statement(s)        none
    Supplemental Hazard        none
    Statements
  Other hazards
    This substance/mixture contains no components considered to be either persistent, bioaccumulative and
    toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

SECTION 3: Composition/information on ingredients
  Substances
    Molecular weight        : 191,18 g/mol
  Hazardous ingredients according to Regulation (EC) No 1272/2008
    Component        Classification        Concentration
  4-Hydroxy-7-Methoxy-1H-Quinolin-2-One
    Acute Tox. 4; H302        <= 100="">
  Hazardous ingredients according to Directive 1999/45/EC
    Component        Classification        Concentration
  4-Hydroxy-7-Methoxy-1H-Quinolin-2-One
    Xn, R22        <= 100="">
    For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

SECTION 4: First aid measures
  Description of first aid measures
  General advice
    Consult a physician. Show this safety data sheet to the doctor in attendance.
  If inhaled
    If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
  In case of skin contact
    Wash off with soap and plenty of water. Consult a physician.
  In case of eye contact
    Flush eyes with water as a precaution.
  If swallowed
    Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
  Most important symptoms and effects, both acute and delayed
    The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
    section 11
  Indication of any immediate medical attention and special treatment needed
    No data available

SECTION 5: Firefighting measures
  Extinguishing media
  Suitable extinguishing media
    Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
  Special hazards arising from the substance or mixture
    Nature of decomposition products not known.
  Advice for firefighters
    Wear self-contained breathing apparatus for firefighting if necessary.
  Further information
    No data available

SECTION 6: Accidental release measures
  Personal precautions, protective equipment and emergency procedures
    Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure
    adequate ventilation. Avoid breathing dust.
    For personal protection see section 8.
  Environmental precautions
    Do not let product enter drains.
  Methods and materials for containment and cleaning up
    Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
    containers for disposal.
  Reference to other sections
    For disposal see section 13.

SECTION 7: Handling and storage
  Precautions for safe handling
    Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
    Provide appropriate exhaust ventilation at places where dust is formed.
    For precautions see section 2.2.
  Conditions for safe storage, including any incompatibilities
    Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
    Storage class (TRGS 510): Non Combustible Solids
  Specific end use(s)
    Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection
  Control parameters
  Components with workplace control parameters
  Exposure controls
  Appropriate engineering controls
    Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
    at the end of workday.
  Personal protective equipment
  Eye/face protection
    Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested
    and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
  Skin protection
    Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
    (without touching glove's outer surface) to avoid skin contact with this product. Dispose of
    contaminated gloves after use in accordance with applicable laws and good laboratory practices.
    Wash and dry hands.
    The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
    the standard EN 374 derived from it.
  Body Protection
    Complete suit protecting against chemicals, The type of protective equipment must be selected
    according to the concentration and amount of the dangerous substance at the specific workplace.
  Respiratory protection
    For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher
    level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges.
    Use respirators and components tested and approved under appropriate government standards
    such as NIOSH (US) or CEN (EU).
  Control of environmental exposure
    Do not let product enter drains.

SECTION 9: Physical and chemical properties
  Information on basic physical and chemical properties
    a) Appearance        Form: solid
    b) Odour        No data available
    c) Odour Threshold        No data available
    d) pH        No data available
    e) Melting point/freezing        No data available
    point
    f) Initial boiling point and No data available
    boiling range
    g) Flash point        No data available
    h) Evaporation rate        No data available
    i) Flammability (solid, gas) No data available
    j) Upper/lower        No data available
    flammability or
    explosive limits
    k) Vapour pressure        No data available
    l) Vapour density        No data available
    m) Relative density        No data available
    n) Water solubility        No data available
    o) Partition coefficient: n- No data available
    octanol/water
    p) Auto-ignition        No data available
    temperature
    q) Decomposition        No data available
    temperature
    r) Viscosity        No data available
    s) Explosive properties        No data available
    t) Oxidizing properties        No data available
  Other safety information
    No data available

SECTION 10: Stability and reactivity
  Reactivity
    No data available
  Chemical stability
    Stable under recommended storage conditions.
  Possibility of hazardous reactions
    No data available
  Conditions to avoid
    No data available
  Incompatible materials
    Strong oxidizing agents
  Hazardous decomposition products
    In the event of fire: see section 5

SECTION 11: Toxicological information
  Information on toxicological effects
  Acute toxicity
    No data available
  Skin corrosion/irritation
    No data available
  Serious eye damage/eye irritation
    No data available
  Respiratory or skin sensitisation
    No data available
  Germ cell mutagenicity
    No data available
  Carcinogenicity
    IARC:        No component of this product present at levels greater than or equal to 0.1% is identified as
    probable, possible or confirmed human carcinogen by IARC.
  Reproductive toxicity
    No data available
  Specific target organ toxicity - single exposure
    No data available
  Specific target organ toxicity - repeated exposure
    No data available
  Aspiration hazard
    No data available
  Additional Information
    RTECS: Not available
    To the best of our knowledge, the chemical, physical, and toxicological properties have not been
    thoroughly investigated.

SECTION 12: Ecological information
  Toxicity
    No data available
  Persistence and degradability
    No data available
  Bioaccumulative potential
    No data available
  Mobility in soil
    No data available
  Results of PBT and vPvB assessment
    This substance/mixture contains no components considered to be either persistent, bioaccumulative and
    toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
  Other adverse effects
    No data available

SECTION 13: Disposal considerations
  Waste treatment methods
  Product
    Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
    with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
  Contaminated packaging
    Dispose of as unused product.

SECTION 14: Transport information
  UN number
    ADR/RID: -        IMDG: -        IATA: -
  UN proper shipping name
    ADR/RID: Not dangerous goods
    IMDG: Not dangerous goods
    IATA:        Not dangerous goods
  Transport hazard class(es)
    ADR/RID: -        IMDG: -        IATA: -
  Packaging group
    ADR/RID: -        IMDG: -        IATA: -
  Environmental hazards
    ADR/RID: no        IMDG Marine pollutant: no        IATA: no
  Special precautions for user
    No data available

SECTION 15: Regulatory information
    This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
  Safety, health and environmental regulations/legislation specific for the substance or mixture
    No data available
  Chemical Safety Assessment

SECTION 16 - ADDITIONAL INFORMATION
N/A