34801-14-4 (2-(2-氨基-4-噻唑基)-5-溴噻吩,4-(5-bromothiophen-2-yl)-1,3-thiazol-2-amine)

快速询单

结构式：

2-(2-氨基-4-噻唑基)-5-溴噻吩MOL文件

CAS号：

34801-14-4

中文名称：

2-(2-氨基-4-噻唑基)-5-溴噻吩

英文名称：

4-(5-bromothiophen-2-yl)-1,3-thiazol-2-amine

分子式：

C₇H₅BrN₂S₂

分子量：

261.161997556686

API：

Avatrombopag

2-(2-氨基-4-噻唑基)-5-溴噻吩(34801-14-4)名称与标识符

名称

中文别名：

4-(5-溴-2-噻吩基)-1,3-噻唑-2-胺;2-(2-氨基-4-噻唑基)-5-溴噻吩;

英文别名：

4-(5-Bromothiophen-2-yl)thiazol-2-amine;2-Thiazolamine,4-(5-bromo-2-thienyl)-;4-(5-BROMOTHIEN-2-YL)-1,3-THIAZOL-2-AMINE;4-(5-BROMOTHIOPHEN-2-YL)THIAZOL-2-YLAMINE;2-(2-Amino-4-thiazolyl)-5-bromothiophene;2-(2-Amino-thiazolyl-4)-5-brom-thiophen;2-Amino-4-(5-brom-2-thienyl)thiazol;2-amino-4-(5-bromo-2-thienyl)-isothiazole;2-amino-4-(5-bromo-2-thienyl)thiazole;4-(5-Bromo-2-thienyl)-1,3-thiazol-2-amine;4-(5-Bromo-2-thienyl)-2-thiazolamine;4-(5-BROMOTHIOPHEN-2-YL)THIAZOL-2-YLAMIN;IFLAB-BB F1386-0416;4-(5-bromothiophen-2-yl)-1,3-thiazol-2-amine;175135-92-9;Maybridge1_001930;2-AMINO-4-(5-BROMOTHIOPHEN-2-YL)THIAZOLE;A822405;4-(5-Bromothiophen-2-yl)-1,3-thiazol-2(3H)-imine;DTXSID70956282;J-019762;MFCD01812622;CS-0200092;J-513589;AS-54617;BRD-K05621897-001-01-7;4-(5-bromo-2-thiophenyl)-2-thiazolamine;SCHEMBL3418282;F0214-0069;HMS546P16;4-(5-Bromo-thiophen-2-yl)-thiazol-2-ylamine;2-amino-4-(5-bromothien-2-yl)thiazole;FT-0616673;EN300-02233;4-(5-bromanylthiophen-2-yl)-1,3-thiazol-2-amine;SC2191;Z48847662;34801-14-4;MMZHPDCFNLBMBY-UHFFFAOYSA-N;AKOS000122285;DB-048684;STK312717;

标识符

MDL：

MFCD01812622

InChIKey：

MMZHPDCFNLBMBY-UHFFFAOYSA-N

Inchi：

1S/C7H5BrN2S2/c8-6-2-1-5(12-6)4-3-11-7(9)10-4/h1-3H,(H2,9,10)

SMILES：

BrC1=CC=C(C2=CSC(N)=N2)S1

2-(2-氨基-4-噻唑基)-5-溴噻吩(34801-14-4)物化性质

实验特性

LogP : 3.79750
PSA : 95.39000
沸点 : 392.1 ℃ at 760 mmHg
熔点 : 151 ºC
蒸气压 : 0.0±0.6 mmHg at 25°C
闪点 : 119.3±21.8 °C
密度 : 1.796

计算特性

精确分子量 : 259.90800
氢键供体数量 : 2
氢键受体数量 : 2
可旋转化学键数量 : 1
同位素质量 : 259.90775g/mol
重原子数量 : 12
复杂度 : 170
同位素原子数量 : 0
确定原子立构中心数量 : 0
不确定原子立构中心数量 : 0
确定化学键立构中心数量 : 0
不确定化学键立构中心数量 : 0
共价键单元数量 : 1
疏水参数计算参考值（XlogP） : 3
拓扑分子极性表面积 : 95.4Å²

2-(2-氨基-4-噻唑基)-5-溴噻吩(34801-14-4)安全信息

安全说明： S26; S36/37/39
风险术语： R20/21/22; R36/37/38
危险品标志： Xn
危害声明：H302;H312;H315;H319;H332;H335
警示性声明：P261;P280;P301+P312;P302+P352;P304+P340;P305+P351+P338
储存条件： Room temperature
危险类别码： R20/21/22;R36/37/38
信号词： Warning

2-(2-氨基-4-噻唑基)-5-溴噻吩(34801-14-4)国际标准相关数据

EINECS：

2-(2-氨基-4-噻唑基)-5-溴噻吩(34801-14-4)海关数据

海关编码：

2934999090

海关数据：

中国海关编码：

2934999090

概述：

2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

申报要素：

品名, 成分含量, 用途

Summary：

2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-(2-氨基-4-噻唑基)-5-溴噻吩(34801-14-4)推荐厂家更多厂家(15)

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2-(2-氨基-4-噻唑基)-5-溴噻吩(34801-14-4)参考资料

Reaxys RN：

PubChem CID：

725239

2-(2-氨基-4-噻唑基)-5-溴噻吩(34801-14-4) MSDS

基础信息

Name:	4-(5-Bromo-2-thienyl)-1 3-thiazol-2-amine 97% Material Safety Data Sheet
Synonym:
CAS:	34801-14-4

Section 1 - Chemical Product ? MSDS Name:4-(5-Bromo-2-thienyl)-1 3-thiazol-2-amine 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
34801-14-4	4-(5-Bromo-2-thienyl)-1,3-thiazol-2-am	97%	unlisted

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
? EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
? Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
? General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
? General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
? Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
? Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 34801-14-4: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
?
Physical State: Solid
Color: off-white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 139 - 141 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C7H5BrN2S2
Molecular Weight: 261

Section 10 - STABILITY AND REACTIVITY
? Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents, acid chlorides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide, hydrogen bromide, bromine.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
? RTECS#:
CAS# 34801-14-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
4-(5-Bromo-2-thienyl)-1,3-thiazol-2-amine - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION
?

Section 13 - DISPOSAL CONSIDERATIONS
? Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
?
IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION
?
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 34801-14-4: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 34801-14-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 34801-14-4 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A