66356-53-4 (2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺,N- Hydro Ranitidine)

快速询单

结构式：

2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺MOL文件

CAS号：

66356-53-4

中文名称：

2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺

英文名称：

N- Hydro Ranitidine

安全信息：

分子式：

C₁₀H₁₈N₂OS

分子量：

214.327721118927

API：

Ranitidine

2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺(66356-53-4)名称与标识符

名称

中文别名：

2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺;5-(((2-氨基乙基)硫代)甲基)-N,N-二甲基-2-呋喃甲胺;2-[[[5-[(二甲氨基)甲基]-2-呋喃基]甲基]硫代]乙胺;2-[(2-氨基乙硫基)甲基]-5-[(N,N-二甲氨基)甲基]呋喃;2-[[[5-[(Dimethylamino)methyl]-2-furyl]methyl]thio]ethylamine 2-[[[5-[(二甲氨基)甲基]-2-呋喃基]甲基]硫代]乙胺;5-(((2-氨基乙基)硫代)甲基)-N,N;雷尼替丁杂质;雷尼替丁杂质B;盐酸雷尼替丁杂质B(EP) 标准品;2[([5-[(二甲胺)甲基]-2-呋喃基]甲基)硫代]乙胺;2-[[(2-氨乙基)硫代]甲基]-5-[(二甲氨基)甲基]呋喃;

英文别名：

2-((5-((Dimethylamino)methyl)furan-2-yl)thio)ethanamine;5-[[(2-Aminoethyl)thio]methyl]-N,N-dimethyl-2-furfurylamine;2-((2-Aminoethylthio)Methyl)-5-((N,N-diMethylamino)Methyl)Furan;2-[[[5-[(Dimethylamino)methyl]-2-furyl]methyl]thio]ethylamine;2-((5-((Dimethylamino)methyl)-furan-2-yl)thio)ethanamine;2-[({5-[(Dimethylamino)methyl]-2-furyl}methyl)thio]ethan-1-amine;2-Furanmethanamine, 5-[[(2-aminoethyl)thio]methyl]-N,N-dimethyl-;Ranitidine Impurity;Ranitidine Impurity B;2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethanamine;2-[[(2-Aminoethyl)thio]methyl]-5-[(dimethylamino)methyl]furan;2-[[5-[(dimethylamino)methyl]-2-furyl]methylsulfanyl]ethanamine;2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethanamine;2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine;AM804206;AC-8815;AKOS015897325;Q27289060;5-[(2-aminoethyl)-thiomethyl]-N,N-di-methyl-2-furanmethanamine;2-(5-dimethylaminomethyl-2-furanylmethylthio)ethyl amine;2-(5-dimethylaminomethylfuran-2-ylmethylthio)ethylamine;2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethylamine;2-[[[5-(Dimethylamino)methyl-2-furanyl]methyl]thio]-ethylamine;2-[[[5-(Dimethylamino) methyl-2-furanyl]methyl]thio]ethanamine;5-[[(2-aminoethyl)thio]methyl]-N,N-dimethyl-furanmethanamine;RANITIDINE HYDROCHLORIDE IMPURITY B [EP IMPURITY];2-[5-(dimethylaminomethyl)-2-furanylmethylthio]ethylamine;S8W8I89W43;MLS006012016;D4749;SMR002530033;SR-01000944863-1;2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethylamine;2-FURANMETHANAMINE, 5-(((2-AMINOETHYL)THIO)METHYL)-N,N-DIMETHYL-;5-[[(2-aminoethyl)thio]methyl]-N,N-dimethyl-2-furanmethanamine;AS-36001;2-(2-Aminoethylthiomethyl)-5-dimethylaminomethylfuran;5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine;NS00004694;2-[[5-[(dimethylamino)methyl]-furfuryl]thio]ethylamine;2-[[[5-(Dimethylamino)methyl-2-furanyl]methyl]-thio]ethylamine;2-(2-dimethylaminomethyl-5-furylmethylthio)ethylamine;FT-0610777;SR-01000944863;5-[[(2-aminoethyl)thio]methyl]N,N-dimethylfuranmethanamine;N-[(5-{[(2-aminoethyl)sulfanyl]methyl}-2-furyl)methyl]-N,N-dimethylamine;EINECS 266-330-4;2-[(5-dimethylaminomethyl-2furanyl)methylthio]ethylamine;2-[[[5-[(Dimethylamino)-methyl]furan-2-yl]methyl]sulphanyl]-ethanamine;AR-011/06455025;2-(5-dimethylaminomethyl-2-furylmethylthio)ethylamine;2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]-ethane amine;CS-0166235;2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethanamine? (Ranitidine Impurity;2-[(5-dimethylaminomethylfuran-2-yl)methylthio]ethylamine;DTXSID20216580;UNII-S8W8I89W43;SCHEMBL7995056;BDBM50158372;N- Hydro Ranitidine;EC 266-330-4;(5-dimethylaminomethyl-2-furylmethylthio] ethylamine;5-[[(2-aminoethyl)thio]methyl]N,N-dimethyl-2-furanmethanamine;2-(((5-((DIMETHYLAMINO)METHYL)FURAN-2-YL)METHYL)SULFANYL)ETHANAMINE;2-(5-dimethylaminomethyl-2-furyl-methylthio)ethylamine;66356-53-4;2-((5-((dimethylamino)methyl)furan-2-yl)methylthio)ethanamine;2-[(5-dimethylaminomethyl-2furyl)methylthio]ethylamine;2-[((5-[(Dimethylamino)methyl]-2-furyl)methyl)sulfanyl]ethanamine #;Ranitidine-d6ImpurityB;CHEMBL3779956;2-[[5-[(dimethylamino)methyl]furfuryl]thio]ethylamine;(5-dimethylaminomethyl-2-furylmethylthio]ethylamine;5-((2-Aminoethyl)thiomethyl)-N,N-dimethyl-2-furanmethanamine;2-(5-dimethylaminomethyl-2-furanylmethylthio)ethylamine;?5-[[(2-Aminoethyl)thio]methyl]-N,N-dimethyl-2-furfurylamine;5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furfurylamine;2-[5-dimethylaminomethylfuran-2-ylmethylthio]ethylamine;2-{[5-Dimethylamino)methylfuryl]thio}ethylamine;MFCD00277202;2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]sulphanyl]ethanamine;2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethanamine;

标识符

MDL：

MFCD23140908

InChIKey：

JFGCGQJHMUYGLU-UHFFFAOYSA-N

Inchi：

1S/C10H18N2OS/c1-12(2)7-9-3-4-10(13-9)8-14-6-5-11/h3-4H,5-8,11H2,1-2H3

SMILES：

S(CCN)CC1=CC=C(CN(C)C)O1

2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺(66356-53-4)物化性质

实验特性

LogP : 2.23340
PSA : 67.70000
折射率 : 1.5300 to 1.5340
沸点 : 106°C/0.1mmHg(lit.)
闪点 : 130.9 °C
颜色与性状 : Liquid
溶解性 : 微溶于水，溶于乙醇，丙酮。
最大波长(λmax) : 228(CH3CN(25vol%))(lit.)
密度 : 1.094

计算特性

精确分子量 : 214.11400
氢键供体数量 : 1
氢键受体数量 : 2
可旋转化学键数量 : 6
同位素质量 : 214.114
重原子数量 : 14
复杂度 : 155
同位素原子数量 : 0
确定原子立构中心数量 : 0
不确定原子立构中心数量 : 0
确定化学键立构中心数量 : 0
不确定化学键立构中心数量 : 0
共价键单元数量 : 1
疏水参数计算参考值（XlogP） : 无
互变异构体数量 : 无
表面电荷 : 0
拓扑分子极性表面积 : 67.7A^2

2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺(66356-53-4)安全信息

符号： GHS07
安全术语： S26;S36/37/39;S45
安全说明： S26; S36/37/39; S45
风险术语： R34
危险品标志： C
危险品运输编号： 2735
危害声明：H315-H319
警示性声明：P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
提示语：警告
储存条件： 2-8 °C
危险类别码： R34
信号词： Danger

2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺(66356-53-4)国际标准相关数据

EINECS：

266-330-4

2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺(66356-53-4)海关数据

海关编码：

2932190090

海关数据：

中国海关编码：

2932190090

概述：

2932190090 其他结构上有非稠合呋喃环化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:20.0%

申报要素：

品名, 成分含量, 用途

Summary：

2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺(66356-53-4)生产方法和用途

用途：

雷尼替丁中间体。

2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺(66356-53-4)推荐厂家更多厂家(46)

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2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺(66356-53-4)上下游

苯乙酰二硫化物半胱胺盐酸盐 5-氯甲基呋喃-2-甲醛 S-(2-氨乙基)硫磺酸 5-[[(2-acetamidoethyl)thio]methyl]-N,N-dimethyl-2-furanmethanamine 5-(二甲基氨基甲基)糠基乙醇.盐酸盐 2-氯乙胺盐酸盐糠醇

2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺(66356-53-4)参考资料

Reaxys RN：

3606996

Beilstein：

D154946

PubChem CID：

253661458

2-(((5-二甲基氨基)甲基)-2-呋喃基)甲基)硫代乙胺(66356-53-4) MSDS

基础信息

Name:	2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine Material Safety Data Sheet
Synonym:
CAS:	66356-53-4

Section 1 - Chemical Product ? MSDS Name:2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
66356-53-4	2-[([5-[(Dimethylamino)methyl]-2-furyl	95+%	266-330-4

Hazard Symbols: C
Risk Phrases: 34

Section 3 - HAZARDS IDENTIFICATION
? EMERGENCY OVERVIEW
Causes burns.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
? Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
? General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide.

Section 6 - ACCIDENTAL RELEASE MEASURES
? General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.

Section 7 - HANDLING and STORAGE
? Handling:
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Corrosives area.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
? Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 66356-53-4: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
?
Physical State: Liquid
Color: yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C10H18N2OS
Molecular Weight: 214

Section 10 - STABILITY AND REACTIVITY
? Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, bases.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide, acrid smoke and fumes.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
? RTECS#:
CAS# 66356-53-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION
?

Section 13 - DISPOSAL CONSIDERATIONS
? Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
?
IATA
Shipping Name: CORROSIVE LIQUID, N.O.S.*
Hazard Class: 8
UN Number: 1760
Packing Group: III
IMO
Shipping Name: CORROSIVE LIQUID, N.O.S.
Hazard Class: 8
UN Number: 1760
Packing Group: III
RID/ADR
Shipping Name: CORROSIVE LIQUID, N.O.S.
Hazard Class: 8
UN Number: 1760
Packing group: III

Section 15 - REGULATORY INFORMATION
?
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 66356-53-4: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 66356-53-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 66356-53-4 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A