753497-20-0 ((Progesterone)

快速询单

结构式：

ProgesteroneMOL文件

CAS号：

753497-20-0

英文名称：

Progesterone

分子式：

C₂₁H₃₀O₂

分子量：

314.461706638336

植物源：

大藨草大藨草

Progesterone(753497-20-0)名称与标识符

名称

英文别名：

progesterone;Agolutin;Luteohormone;Crinone;Corpus luteum hormone;Syngesterone;Utrogestan;Luteol;Glanducorpin;Pregnenedione;Progesterol;Syngestrets;Corlutin;Cyclogest;Gesterol;Gestone;Gestormone;Progestin;Progestone;Progestron;Prometrium;Hormoflaveine;Methylpregnone;Progestasert;Progesteronum;Progestronol;Corlutina;Corluvite;Corporin;Flavolutan;Fologenon;Gynlutin;Gynolutone;Hormoluton;Lingusorbs;Lucorteum;Luteodyn;Luteogan;Luteopur;Luteosan;Lut;

标识符

InChIKey：

RJKFOVLPORLFTN-LEKSSAKUSA-N

Inchi：

1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1

SMILES：

O=C(C)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(CC[C@]4(C)[C@H]3CC[C@@]21C)=O

Progesterone(753497-20-0)物化性质

计算特性

氢键供体数量 : 0
氢键受体数量 : 2
可旋转化学键数量 : 1
重原子数量 : 23
复杂度 : 589
疏水参数计算参考值（XlogP） : 3.9
拓扑分子极性表面积 : 34.1

Progesterone(753497-20-0)相关文献

1. The conformation of the side chain in cortisone and related compounds; an infra red and nuclear magnetic resonance study
W. G. Cole,Dudley H. Williams J. Chem. Soc. C 1968 1849
2. Synthesis, characterization and in vitro cytotoxic activities of new steroidal thiosemicarbazones and thiadiazolines
Marijana B. ?ivkovi?,Ivana Z. Mati?,Marko V. Rodi?,Irena T. Novakovi?,Du?an M. Sladi?,Natalija M. Krsti? RSC Adv. 2016 6 34312
3. Fractionation of an antiserum to progesterone by affinity chromatography: effect of pH, solvents and biospecific adsorbents
Cornelia Parini,Maria A. Bacigalupo,Stefano Colombi,Nadia Corocher,Claudio Baggiani,Gianfranco Giraudi Analyst 1995 120 1153
4. Preparation and decomposition of some steroidal 4′β,5′-dihydro-[17α,16-c]pyrazoles
Peter Bladon,Duncan R. Rae,Alexander D. Tait J. Chem. Soc. Perkin Trans. 1 1974 1468
5. Synthesis of conjugates of 11α-hydroxyprogesterone with β-nicotinamide adenine dinucleotide (β-NAD) and adenosine triphosphate (ATP)
David N. Kirk,Barry W. Miller J. Chem. Soc. Perkin Trans. 1 1988 2983
6. Synthesis of [19-2H3]progesterone and [18-2H3]progesterone
David N. Kirk,Carmen Z. Smith,Michael J. Varley,John W. Honour J. Chem. Soc. Perkin Trans. 1 1990 2745
7. A survey of the high-field 1H NMR spectra of the steroid hormones, their hydroxylated derivatives, and related compounds
David N. Kirk,Harold C. Toms,Christal Douglas,Karen A. White,Kelvin E. Smith,Shahid Latif,Robert W. P. Hubbard J. Chem. Soc. Perkin Trans. 2 1990 1567
8. 4. Modified steroid hormones. Part XXV. 16α-Acetoxy-, 16α-methyl, and 16β-methyl derivatives of 17α-acetoxy-6-methylpregna-4,6-diene-3,20-dione
B. Ellis,S. P. Hall,V. Petrow,D. M. Williamson J. Chem. Soc. 1962 22
9. New syntheses of 19,21-dihydroxypregn-4-ene-3,20-dione, 21-hydroxy-19-norpregn-4-ene-3,20-dione, and 11β,19,21-trihydroxypregn-4-ene-3,20-dione
David N. Kirk,Boon Leng Yeoh J. Chem. Soc. Perkin Trans. 1 1983 2945
10. Novel glucocorticoid antedrugs possessing a 21-(γ-lactone) ring
Richard M. Angell,Keith Biggadike,Rosanne M. Farrell,Stephen S. Flack,Ashley P. Hancock,Wendy R. Irving,Sean M. Lynn,Panayiotis A. Procopiou J. Chem. Soc. Perkin Trans. 1 2002 831