86-51-1 (2,3-二甲氧基苯甲醛,2,3-Dimethoxybenzaldehyde)

反应条件：

1.1 Reagents: Phosphonium, triphenyl(phenylmethyl)-, chlorate (1:1) Catalysts: Aluminum chloride Solvents: Acetonitrile

参考文献：

Oxidation of alcohols with benzyltriphenylphosphonium chlorate under non-aqueous conditions

Hajipour, A. R.; et al, Phosphorus, 2001, 176, 1-7

合成路线：1 步

5653-67-8

_98%

反应条件：

1.1 Reagents: Oxygen Catalysts: Potassium tert-butoxide , Tempo , Copper bromide (CuBr2) , Poly[oxy(dimethylsilylene)], α-[dimethyl[3-[(2-pyridinylmethylene)amino]propyl]s… Solvents: Acetonitrile , Water ; 4 h, 25 °C

参考文献：

Room temperature aerobic oxidation of alcohols using CuBr2 with TEMPO and a tetradentate polymer based pyridyl-imine ligand

Hu, Zhenzhong; et al, Applied Catalysis, 2012, 413, 413-414

合成路线：1 步

5653-67-8

_98%

反应条件：

1.1 Reagents: 4-Aza-1-azoniabicyclo[2.2.2]octane, 1-butyl-, (T-4)-chlorotrioxochromate(1-) Catalysts: Aluminum chloride Solvents: Acetonitrile ; 2 h, reflux

参考文献：

Oxidation of alcohols with 1-butyl-4-aza-1-azoniabicyclo[2.2.2]octane chlorochromate (BAAOCC) under non-aqueous conditions

Hajipour, Abdol R.; et al, Indian Journal of Chemistry, 2005, (3), 577-580

合成路线：1 步

1214-54-6

75-16-1

_99%

反应条件：

1.1 Solvents: Tetrahydrofuran ; rt → 0 °C
1.2 Solvents: Tetrahydrofuran ; 0 °C → rt
1.3 Reagents: Hydrochloric acid Solvents: Water ; rt

参考文献：

Probing Persistent Intramolecular C-H···X (X = O, S, Br, Cl, and F) Bonding in Solution Using Benzyl Meldrum's Acid Derivatives

Fillion, Eric; et al, Journal of Organic Chemistry, 2009, 74(3), 1259-1267

合成路线：1 步

_99%

反应条件：

1.1 Reagents: Potassium carbonate Solvents: Dimethylformamide ; 42 h, 45 °C

参考文献：

Synthesis and Properties of Bimetallic Hoveyda-Grubbs Metathesis Catalysts

Grudzien, Krzysztof; et al, Organometallics, 2012, 31(9), 3636-3646

合成路线：1 步

_98%

反应条件：

1.1 Reagents: Potassium carbonate Solvents: Dimethylformamide ; 16 h, 60 °C

参考文献：

New short synthesis of (5)-2,3-dimethoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-iodobenzamide. Dopamine D2 receptor

Joshua, Alummoottil V.; et al, Synthetic Communications, 2008, 38(3), 434-440

合成路线：1 步

_79%

反应条件：

1.1 Reagents: Potassium carbonate Solvents: Dimethylformamide ; 23 h, 60 °C

参考文献：

Studies on synthesis of quinonylidene Hoveyda-type complexes

Grudzien, Krzysztof; et al, Applied Organometallic Chemistry, 2015, 29(5), 322-327

合成路线：1 步

77-78-1

_99%

反应条件：

1.1 Reagents: Potassium carbonate Solvents: Benzene

参考文献：

A synthesis of the phenolic lipid, 3-[(Z)-pentadec-8-enyl] catechol, (15:1)-urushiol

Tyman, John H. P.; et al, Chemistry and Physics of Lipids, 2002, 120(1-2), 101-108

合成路线：1 步

77-78-1

_84%

反应条件：

1.1 Reagents: Potassium hydroxide Solvents: Water

参考文献：

The 2-aminotetralin system as a structural base for new dopamine- and melatonin-receptor agents

Copinga, Swier, 1994, , ,

合成路线：1 步

77-78-1

参考文献：

Electron-impact induced loss of C-5 and C-8 substituents in 1,2,3,4-tetrahydroisoquinolines. II: Synthesis of C-8 substituted 1,2,3,4-tetrahydroisoquinolines

Mayer, Klaus K.; et al, Archiv der Pharmazie (Weinheim, 1983, 316(9), 801-12

合成路线：1 步

216664-07-2

_97%

反应条件：

1.1 Reagents: Boron tribromide Solvents: Dichloromethane

参考文献：

Synthesis of Potentially Carcinogenic Higher Oxidized Metabolites of Dibenz[a,j]anthracene and Benzo[c]chrysene

Harvey, Ronald G.; et al, Journal of Organic Chemistry, 1998, 63(23), 8118-8124

合成路线：1 步

616-38-6

_90%

反应条件：

1.1 Catalysts: Potassium carbonate ; rt → 150 °C; 11 h, 150 °C

参考文献：

Study on green synthesis of O-veratraldehyde

Pan, Shu-gang; et al, Anhui Nongye Kexue, 2009, 37(1), 13-15

合成路线：1 步

560094-94-2

_90%

反应条件：

1.1 Catalysts: Bismuth triflate Solvents: Dichloromethane , Water ; 10 min, rt

参考文献：

An efficient catalytic deprotection of thioacetals employing bismuth triflate: synthesis of pyrrolo[2,1-c] [1,4] benzodiazepines

Kamal, Ahmed; et al, Tetrahedron Letters, 2003, 44(14), 2857-2860

合成路线：1 步

213479-69-7

10210-68-1

_83%

反应条件：

1.1 Reagents: Sodium acetate , Triethylsilane Catalysts: Dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane addu… Solvents: Acetonitrile ; 16 h, rt

参考文献：

Palladium-catalyzed reductive carbonylation of (hetero)aryl halides and triflates using cobalt carbonyl as CO source

Dogga, Bhushanarao; et al, European Journal of Organic Chemistry, 2021, 2021(2), 309-313

合成路线：1 步

213479-69-7

10210-68-1

_72%

反应条件：

1.1 Reagents: Potassium acetate , Triethylsilane Catalysts: Palladium diacetate , 1,1′-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis[1,1-diphenylphosphine] Solvents: 1,4-Dioxane ; 12 h, 50 °C

参考文献：

Room Temperature Carbonylation of (Hetero) Aryl Pentafluorobenzenesulfonates and Triflates using Palladium-Cobalt Bimetallic Catalyst: Dual Role of Cobalt Carbonyl

Joseph, Jayan T.; et al, Advanced Synthesis & Catalysis, 2017, 359(3), 419-425

合成路线：1 步

25245-33-4

64-18-6

_82%

反应条件：

1.1 Reagents: Triphenylphosphine , Iodine Solvents: Toluene ; 10 min, rt
1.2 Reagents: Triethylamine Catalysts: Palladium diacetate ; 4 h, 80 °C

参考文献：

Palladium-Catalyzed Formylation of Aryl Iodides with HCOOH as CO Source

Sun, Guanglong; et al, Organic Letters, 2017, 19(16), 4235-4238

合成路线：1 步

24677-78-9

_73%

反应条件：

1.1 Reagents: Potassium carbonate Solvents: Dimethylformamide ; 1 h, 80 °C

参考文献：

Design, synthesis and evaluation of curcumin-based fluorescent probes to detect Aβ fibrils

Sato, Taki; et al, Bioorganic & Medicinal Chemistry Letters, 2018, 28(22), 3520-3525

合成路线：1 步

106686-63-9

_72%

反应条件：

1.1 Reagents: Sulfuric acid , Dipotassium chromate (K2CrO4) Solvents: Water

参考文献：

The synthesis of 2,3-dimethoxybenzaldehyde (ο-veratraldehyde)

Nagai, Yoshio; et al, Nippon Kagaku Kaishi (1921-47), 1952, , 45-6

合成路线：1 步

1521-38-6

_63%

反应条件：

1.1 Reagents: Chlorotrimethylsilane , Triethylamine Solvents: Dichloromethane
1.2 Reagents: Diisobutylaluminum hydride

参考文献：

One pot conversion of carboxylic acids to aldehydes with DIBAL-H

Chandrasekhar, S.; et al, Tetrahedron Letters, 1998, 39(8), 909-910

合成路线：1 步

1521-38-6

参考文献：

Aliphatic and alicyclic aldehydes: synthesis by reduction or by reduction followed by hydrolysis

Harcken, C., Science of Synthesis, 2007, 25, 65-135

合成路线：1 步

反应条件：

1.1 Reagents: Dimethyl sulfate , Potassium carbonate Solvents: Acetone

参考文献：

Synthesis of β-(2,3-dihydroxybenzoyl)butyric acid

Wang, Dexin; et al, Huaxue Xuebao, 1986, 44(7), 692-4

合成路线：1 步

93-51-6

参考文献：

A new synthesis of anthraquinones using dihydrooxazoles and grignard reagents derived from Mg(anthracene)(THF)3

Nicoletti, Teresa M.; et al, Journal of the Chemical Society, 1990, (1), 133-8

合成路线：1 步

94936-90-0