92944-71-3 (二苯甲酮-4-马来酰亚胺,4-(Maleimido)benzophenone)

_80%

反应条件：

1.1 Reagents: Acetic anhydride , Sodium acetate

参考文献：

Rational Design of Calpain Inhibitors Based on Calpastatin Peptidomimetics

Low, Kristin E.; Ler, Spencer; Chen, Kevin J.; Campbell, Robert L.; Hickey, Jennifer L.; et al, Journal of Medicinal Chemistry, 2016, 59(11), 5403-5415

合成路线：1 步

_74%

反应条件：

1.1 Solvents: Diethyl ether ; rt; rt → reflux; 8 h, reflux
1.2 Reagents: Acetic anhydride , Sodium acetate ; 5 h, 80 °C

参考文献：

Through-Space Charge-Transfer Thermally Activated Delayed Fluorescence Alternating Donor-Acceptor Copolymers for Nondoped Solution-Processable OLEDs

Belousov, George K.; Vaitusionak, Aliaksei A.; Vasilenko, Irina V.; Ghasemi, Melika ; Andruleviciene, Viktorija; et al, Macromolecules (Washington, 2023, 56(7), 2686-2699

合成路线：1 步

_65%

反应条件：

1.1 Solvents: Toluene ; 3 h, reflux
1.2 Reagents: Sodium acetate Solvents: Acetic anhydride ; 2 h, reflux
1.3 Reagents: Sodium bicarbonate ; neutralized

参考文献：

Synthesis and characterization of styrene/maleimide copolymers with high poling stability of dipolar chromophore

Arora, S.; Kumar, S., Optoelectronics and Advanced Materials, 2009, 3(12), 1359-1364

合成路线：1 步

941-69-5

98-88-4

_54%

参考文献：

Reaction of acyl chlorides with N-phenylimides of maleic and itaconic acids

Sanzhizhapov, D. B.; Mognonov, D. M.; Khakhinov, V. V.; Radnaeva, L. D.; Erdyneev, N. S., Izvestiya Sibirskogo Otdeleniya Akademii Nauk SSSR, 1984, (4), 118-20

合成路线：1 步

_29%

反应条件：

1.1 Solvents: Diethyl ether ; 1 h, reflux
1.2 Reagents: Sodium acetate Solvents: Acetic anhydride ; 0.5 h, 90 °C
1.3 Reagents: Water ; cooled

参考文献：

Design, synthesis and biochemical evaluation of novel ethanoanthracenes and related compounds to target Burkitt's lymphoma

Byrne, Andrew J.; Bright, Sandra A.; McKeown, James P.; O'Brien, John E.; Twamley, Brendan; et al, Pharmaceuticals, 2020, 13(1),

合成路线：1 步

304456-51-7

反应条件：

1.1 Reagents: Acetic anhydride , Sodium acetate ; 30 min, 95 °C; 95 °C → rt
1.2 Solvents: Water ; 30 min, cooled

参考文献：

Effect of Polymerizable Photoinitiators on the UV-polymerization behaviors of photosensitive polysiloxane

Jiang, Bo; Zhang, Tong; Zhao, Liwei; Xu, Zhiming; Huang, Yudong, Journal of Polymer Science, 2017, 55(10), 1696-1705

合成路线：1 步

参考文献：

Antineoplastic cytotoxic agent conjugates with transferrin, albumin and polyethylene glycol

, World Intellectual Property Organization, , ,

合成路线：1 步

参考文献：

Antineoplastic transferrin and albumin conjugates of cytostatic compounds selected from anthracyclines, alkylating agents, antimetabolites, and cisplatin analogs

, Germany, , ,

合成路线：1 步

参考文献：

Synthesis of new bifunctional maleimide compounds for the preparation of chemoimmunoconjugates

Beyer, U.; Kruger, M.; Schumacher, P.; Unger, C.; Kratz, F., Monatshefte fuer Chemie, 1997, 128(1), 91-102

合成路线：1 步