93-04-9 (β-萘甲醚,2-Methoxynaphthalene)

947-62-6

反应条件：

1.1 Reagents: Carbon dioxide , Triphenylphosphine , Tetraethylammonium p-toluenesulfonate Catalysts: Dichlorobis(triphenylphosphine)palladium Solvents: Dimethylformamide

参考文献：

Palladium(0)-catalyzed electroreductive carboxylation of aryl halides, β-bromostyrene, and allyl acetates with carbon dioxide

Torii, Sigeru; Tanaka, Hideo; Hamatani, Takeshi; Morisaki, Kazuo; Jutand, Anny; et al, Chemistry Letters, 1986, (2), 169-72

合成路线：1 步

80-48-8

_100%

反应条件：

1.1 Reagents: Sodium hydroxide , 1-Pentanaminium, N-(carboxymethyl)-N,N-dipentyl-, inner salt Solvents: Water ; 8 h, 80 °C

参考文献：

Aqueous reaction solvent containing carboxybetains used for organic chemistry

, Japan, , ,

合成路线：1 步

3401-47-6

_100%

反应条件：

1.1 Reagents: Tripotassium phosphate Catalysts: Palladium diacetate , Dicyclohexyl[4-methoxy-3-(2-methoxyphenyl)-2-naphthalenyl]phosphine Solvents: Methanol , Benzene ; 16 h, 40 °C

参考文献：

A mixed naphthyl-phenyl phosphine ligand motif for Suzuki, Heck, and hydrodehalogenation reactions

Demchuk, Oleg M.; Yoruk, Bilge; Blackburn, Tom; Snieckus, Victor, Synlett, 2006, (18), 2908-2913

合成路线：1 步

616-38-6

_100%

反应条件：

1.1 Catalysts: 1-Ethyl-3-methylimidazolium bromide ; rt; rt → 120 °C; 2.8 h, 120 °C

参考文献：

Catalytic O-methylation of phenols with dimethyl carbonate to aryl methyl ethers using [BMIm]Cl

Shen, Zhen Lu; Jiang, Xuan Zhen; Mo, Wei Min; Hu, Bao Xiang; Sun, Nan, Green Chemistry, 2005, 7(2), 97-99

合成路线：1 步

616-38-6

_99%

反应条件：

1.1 Catalysts: Dimanganese decacarbonyl ; 1 h, 180 °C

参考文献：

Methylation of phenol and its derivatives with dimethyl carbonate in the presence of Mn2(CO)10, W(CO)6, and Co2(CO)8

Khusnutdinov, R. I.; Shchadneva, N. A.; Mayakova, Yu. Yu., Russian Journal of Organic Chemistry, 2015, 51(3), 330-334

合成路线：1 步

_99%

反应条件：

1.1 Reagents: Sodium hydroxide Solvents: 1,2-Dichloroethane , Water ; 0.5 h, 50 - 60 °C; 3 - 5 h, 60 °C → 40 °C

参考文献：

Preparation of DL-naproxen

, China, , ,

合成路线：1 步

5111-65-9

_99%

反应条件：

1.1 Reagents: Tetrabutylammonium bromide Catalysts: Nickel alloy, base, Ni 95,Ag 5 Solvents: Water ; 24 h, 80 °C

参考文献：

Preparation of a cost-effective Ni-Ag bimetallic catalyst for hydrodehalogenation of aryl halides under mild conditions

Deng, Jiazhu; Xue, Teng; Wu, Haihong; Wu, Peng, New Journal of Chemistry, 2022, 46(25), 12169-12176

合成路线：1 步

616-38-6

_99%

反应条件：

1.1 Catalysts: Dimethyl sulfide Solvents: Dimethyl carbonate ; 4 h, rt → 220 °C

参考文献：

Methylation with Dimethyl Carbonate/Dimethyl Sulfide Mixtures: An Integrated Process without Addition of Acid/Base and Formation of Residual Salts

Lui, Yuen Wai; Chan, Bun ; Lui, Matthew Y., ChemSusChem, 2022, 15(3),

合成路线：1 步

74-88-4

_99%

反应条件：

1.1 Reagents: Potassium carbonate Solvents: Dimethylformamide ; rt; 2 h, rt
1.2 Reagents: Hydrochloric acid Solvents: Water ; rt

参考文献：

C-H Nickelation of Naphthyl Phosphinites: Electronic and Steric Limitations, Regioselectivity, and Tandem C-P Functionalization

Mangin, Loic P.; Zargarian, Davit, Organometallics, 2019, 38(24), 4687-4700

合成路线：1 步

67-56-1

_99%

反应条件：

1.1 0.15 MPa, 290 °C

参考文献：

Process for continuously preparing β-naphthyl methyl ether

, China, , ,

合成路线：1 步

55090-57-8

_99%

反应条件：

1.1 Reagents: Poly(methylhydrosiloxane) Catalysts: Nickel acetate tetrahydrate , 1,2-Bis(dicyclohexylphosphino)ethane Solvents: Toluene ; 24 h, 170 °C

参考文献：

Selective Reductive Removal of Ester and Amide Groups from Arenes and Heteroarenes through Nickel-Catalyzed C-O and C-N Bond Activation

Yue, Huifeng; Guo, Lin; Lee, Shao-Chi; Liu, Xiangqian; Rueping, Magnus, Angewandte Chemie, 2017, 56(14), 3972-3976

合成路线：1 步

104116-17-8

_99%

反应条件：

1.1 Reagents: Potassium tert-butoxide Catalysts: [1,3-Bis[2,6-bis(1-methylethyl)phenyl]-2-imidazolidinylidene]chloro(η5-2,4-cyclo… Solvents: Isopropanol ; 24 h, 25 °C

参考文献：

Highly active, well-defined (cyclopentadiene)(N-heterocyclic carbene)palladium chloride complexes for room-temperature Suzuki-Miyaura and Buchwald-Hartwig cross-coupling reactions of aryl chlorides and deboronation homocoupling of arylboronic acids

Jin, Zhong; Guo, Su-Xian; Gu, Xiao-Peng; Qiu, Ling-Ling; Song, Hai-Bing; et al, Advanced Synthesis & Catalysis, 2009, 351(10), 1575-1585

合成路线：1 步

_99%

反应条件：

1.1 Reagents: Sodium carbonate
1.2 Reagents: Polyethylene glycol

参考文献：

Etherification of phenols catalyzed by solid-liquid phase transfer catalyst PEG-400 without solvent

Cao, Yu-Qing; Pei, Ben-Gao, Synthetic Communications, 2000, 30(10), 1759-1766

合成路线：1 步

3401-47-6

_98%

反应条件：

1.1 Reagents: 1,8-Diazabicyclo[5.4.0]undec-7-ene Catalysts: 9-Hydroxy-1H-phenalen-1-one Solvents: Dimethyl sulfoxide ; 12 h, rt

参考文献：

Transforming Non-innocent Phenalenyl to a Potent Photoreductant: Captivating Reductive Functionalization of Aryl Halides through Visible-Light-Induced Electron Transfer Processes

Pathania, Vishali ; Roy, Vishal Jyoti; Roy, Sudipta Raha, Journal of Organic Chemistry, 2022, 87(24), 16550-16566

合成路线：1 步

5111-65-9

_98%

反应条件：

1.1 Reagents: 4-Methylmorpholine , Diboronic acid Catalysts: Palladium Solvents: 1,2-Dichloroethane ; 3 h, 50 °C

参考文献：

Catalytic Reductions Without External Hydrogen Gas: Broad Scope Hydrogenations with Tetrahydroxydiboron and a Tertiary Amine

Korvinson, Kirill A.; Akula, Hari K.; Malinchak, Casina T.; Sebastian, Dellamol; Wei, Wei; et al, Advanced Synthesis & Catalysis, 2020, 362(1), 166-176

合成路线：1 步

580-13-2

67-56-1

_98%

反应条件：

1.1 Reagents: Triethylamine Catalysts: Cadmium sulfide , Nickel dichloride , 4,4′-Bis(1,1-dimethylethyl)-2,2′-bipyridine Solvents: Dimethylacetamide ; rt

参考文献：

Practical heterogeneous photoredox/nickel dual catalysis for C-N and C-O coupling reactions

Liu, Yi-Yin; Liang, Dong; Lu, Liang-Qiu; Xiao, Wen-Jing, Chemical Communications (Cambridge, 2019, 55(33), 4853-4856

合成路线：1 步

_98%

反应条件：

1.1 Reagents: Sodium hydroxide Solvents: Dimethylformamide ; 25 °C
1.2 2 h, 25 °C

参考文献：

Synthesis of 6-propyl-2-naphthol

Li, Yan-yan; Liu, Qian-feng, Yingyong Huagong, 2014, 43(5), 901-904

合成路线：1 步

67-56-1

_98%

反应条件：

1.1 Catalysts: Carbon , Sulfuric acid Solvents: Benzene ; 15 min, 80 °C

参考文献：

Synthesis of β-naphthyl methyl ether catalyzed by activated carbon modified by H2SO4 under ultrasonic irradiation

Xiao, Dongcai; Yang, Jinhui, Jingxi Huagong, 2010, 27(10), 1038-1040

合成路线：1 步

67886-70-8

_98%

反应条件：

1.1 Reagents: Triisopropylsilane Catalysts: Tributyl phosphite , Di-μ-chlorobis[(1,2,5,6-η)-1,5-cyclooctadiene]dirhodium Solvents: Ethylcyclohexane ; 15 h, 130 °C

参考文献：

Rhodium-catalyzed carbon-cyano bond cleavage reactions using organosilicon reagents

Kita, Yusuke; Tobisu, Mamoru; Chatani, Naoto, Yuki Gosei Kagaku Kyokaishi, 2010, 68(11), 1112-1122

合成路线：1 步

67886-70-8

_98%

反应条件：

1.1 Reagents: Triisopropylsilane Catalysts: Triisopropyl phosphite , Di-μ-chlorobis[(1,2,5,6-η)-1,5-cyclooctadiene]dirhodium Solvents: Ethylcyclohexane ; 15 h, 130 °C

参考文献：

Rhodium-catalyzed reductive decyanation of nitriles using hydrosilane as a reducing agent: scope, mechanism and synthetic application

Tobisu, Mamoru; Nakamura, Ryo; Kita, Yusuke; Chatani, Naoto, Bulletin of the Korean Chemical Society, 2010, 31(3), 582-587

合成路线：1 步

_98%