931-23-7 (羟基丁烯内酯,Hydroxybutenolide)

反应条件：

1.1 Reagents: Hydrochloric acid Solvents: Water ; 48 h, 100 °C

参考文献：

(PCy3)2Cl2Ru:CHPh- Catalyzed Kharasch additions. Application in a formal olefin carbonylation

Lee, Belinda T.; Schrader, Thomas O.; Martin-Matute, Belen; Kauffman, Christopher R.; Zhang, Peng; et al, Tetrahedron, 2004, 60(34), 7391-7396

合成路线：1 步

203131-27-5

_87%

反应条件：

1.1 Reagents: Amberlyst 15 Solvents: Water

参考文献：

A mild, efficient, and general method for the synthesis of trialkylsilyl (Z)-4-oxo-2-alkenoates and γ-hydroxybutenolides

Boukouvalas, John; Lachance, Nicolas, Synlett, 1998, (1), 31-32

合成路线：1 步

138689-96-0

_79%

反应条件：

1.1 Reagents: Sodium hydroxide Solvents: Ethanol
1.2 Reagents: Formaldehyde
1.3 Reagents: Hydrochloric acid Solvents: 1,4-Dioxane

参考文献：

Synthesis of useful functionalized prenyl derivatives in the E or Z configuration

Solladie, Guy; Berl, Valerie, Synlett, 1991, (11), 795-6

合成路线：1 步

51799-96-3

_75%

反应条件：

1.1 Reagents: Potassium hydroxide Solvents: Water ; 3 h, rt
1.2 Reagents: Hydrochloric acid Solvents: Water

参考文献：

Structural Requirements of Strigolactones for Hyphal Branching in AM Fungi

Akiyama, Kohki; Ogasawara, Shin; Ito, Seisuke; Hayashi, Hideo, Plant and Cell Physiology, 2010, 51(7), 1104-1117

合成路线：1 步

_65%

反应条件：

1.1 Reagents: Phenylboronic acid Solvents: Water ; 16 h, 100 °C

参考文献：

Synthesis of Analogs of Strigolactones and Evaluation of Their Stability in Solution

Blanco-Ania, Daniel; Zwanenburg, Binne, Methods in Molecular Biology (New York, 2021, 2309, 37-55

合成路线：1 步

71589-47-4

_65%

反应条件：

1.1 Reagents: Acetic acid , Hydrochloric acid Solvents: Ethanol , Water ; 4 h, rt → reflux

参考文献：

Methods for hydraulic enhancement of crops

, World Intellectual Property Organization, , ,

合成路线：1 步

80350-42-1

_65%

反应条件：

1.1 Reagents: Hydrochloric acid Solvents: Ethanol , Acetic acid ; 4 h, rt → reflux
1.2 Solvents: Water ; rt → 90 °C; 45 min, 90 °C

参考文献：

Strigolactone formulations and uses thereof

, World Intellectual Property Organization, , ,

合成路线：1 步

_60%

反应条件：

1.1 Reagents: Sulfuric acid Solvents: Water ; 16 h, reflux

参考文献：

Preparation and application of lactone analogs with indolin-2-one skeleton

, China, , ,

合成路线：1 步

5143-08-8

5143-07-7

_60%

反应条件：

1.1 Reagents: Ozone Solvents: Dichloromethane
1.2 Reagents: Triphenylphosphine
1.3 Reagents: (Carbethoxyethylidene)triphenylphosphorane
1.4 Reagents: Hydrochloric acid Solvents: 1,4-Dioxane , Water

参考文献：

2,5-Dimethoxy-2,5-dihydrofuran: a convenient synthon for a novel mono-protected glyoxal; synthesis of 4-hydroxybutenolides

Fell, Stephen C. M.; Harbridge, John B., Tetrahedron Letters, 1990, 31(29), 4227-8

合成路线：1 步

_52%

反应条件：

1.1 Reagents: Sulfuric acid Solvents: Water ; rt; 16 h, reflux

参考文献：

Preparation of thioether strigolactone derivatives and its application as plant growth regulator

, China, , ,

合成路线：1 步

_52%

反应条件：

1.1 Reagents: Sulfuric acid Solvents: Water ; rt; 16 h, reflux

参考文献：

Preparation of furanyl oxime ether compounds and application thereof

, China, , ,

合成路线：1 步

_52%

反应条件：

1.1 Reagents: Sulfuric acid Solvents: Water ; rt; 16 h, rt → reflux

参考文献：

Alkenyl ether compound with strigolactone activity and application thereof for plant growth regulator

, China, , ,

合成路线：1 步

_52%

反应条件：

1.1 Catalysts: Sulfuric acid Solvents: Water ; rt; 16 h, reflux

参考文献：

Synthesis of highly enantio-enriched stereoisomers of hydroxy-GR24

Morris, J. C.; McErlean, C. S. P., Organic & Biomolecular Chemistry, 2016, 14(4), 1236-1238

合成路线：1 步

71589-47-4

_47%

反应条件：

1.1 Reagents: Hydrochloric acid

参考文献：

Friedel-Crafts reactions of aromatic derivatives with 1,4-dioxo 2,3-ethylenic compounds. IV. Reactions of 5-hydroxy- or 5-chloro-3,5-dimethyl- or -4,5-dimethyl-2(5H)-furanones

Canevet, Jean Claude; Graff, Yves, Helvetica Chimica Acta, 1979, 62(5), 1614-21

合成路线：1 步

_36%

反应条件：

1.1 Catalysts: Sulfuric acid Solvents: Water ; 12 h, 110 °C

参考文献：

Enantioselective Acetalization by Dynamic Kinetic Resolution for the Synthesis of γ-Alkoxybutenolides by Thiourea/Quaternary Ammonium Salt Catalysts: Application to Strigolactones

Yasui, Motohiro ; Yamada, Ayano; Tsukano, Chihiro ; Hamza, Andrea ; Papai, Imre; et al, Angewandte Chemie, 2020, 59(32), 13479-13483

合成路线：1 步

32663-81-3

_35%

反应条件：

1.1 Reagents: Hydrochloric acid

参考文献：

Carotenoids and related compounds. XVIII. Synthesis of cis- and cis, cis-polyenes by reactions of the Wittig type

Pattenden, Gerald; Weedon, B. C. L., Journal of the Chemical Society [Section] C: Organic, 1968, (16), 1984-97

合成路线：1 步

_30%

反应条件：

1.1 Catalysts: Acetic acid Solvents: Tetrahydrofuran , Water ; 26 h, 120 °C; cooled

参考文献：

A new expedient synthesis of 3-methyl-2(5H)-furanone, the common substructure in strigolactones, and its proposed biosynthesis

Malik, Heetika; Rutjes, Floris P. J. T.; Zwanenburg, Binne, Synthesis, 2010, (19), 3271-3273

合成路线：1 步

反应条件：

1.1 Reagents: Hydrochloric acid Solvents: Water ; rt; rt → reflux; 16 h, reflux

参考文献：

Indole-3-carboxylate strigolactone analog compound capable of promoting germination of parasitic plant seed, and preparation method thereof based on indole-3-carboxylic acid

, China, , ,

合成路线：1 步

反应条件：

1.1 Reagents: Hydrochloric acid Solvents: Water ; rt → reflux; 16 h, reflux

参考文献：

Compound capable of bidirectionally regulating plant growth and its preparation

, China, , ,

合成路线：1 步